Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Rat (Rattus) Antikörper:
anti-Mouse (Murine) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal Vcan Primary Antibody für ICC, IF - ABIN4365244
Van Bockstal, Lambein, Van Gele, De Vlieghere, Limame, Braems, Van den Broecke, Cocquyt, Denys, Bracke, Libbrecht, De Wever: Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion. in Oncoscience 2015
The isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones.
Data show that expression of mRNAs for aggrecan (zeige ACAN Antikörper), collagen type II, and versican were significantly effected by the intervention.
Data show that biglycan (zeige BGN Antikörper), collagen type I, collagen type II, decorin (zeige DCN Antikörper), and versican were significantly affected by vibration duration, frequency, and amplitude.
This study highlights the oncogenic role of VCAN in renal cell carcinogenesis and suggests that this gene has therapeutic and/or biomarker potential for renal cell cancer.
Interleukin-17A (zeige IL17A Antikörper) promotes tongue squamous cell carcinoma metastasis by activating miR (zeige MLXIP Antikörper)-23b/versican pathway in the tumor microenvironment.
The macular dysfunction on mfERG was profound and of early onset. A heterozygous mutation in intron 7 of the VCAN gene (c.4004-1G > A) was found.
Versican V0 and V1 isoforms were upregulated in the uterine leiomyomas of symptomatic versus asymptomatic women. Abundant cleaved versican was detected in leiomyoma and myometrium, as well as in myometrial and leiomyoma cell lines. VCAN siRNA did not effect cell proliferation, apoptosis, or smooth muscle markers, but reduced ESR1 (zeige ESR1 Antikörper) and PR-A (zeige PGR Antikörper) expression.
Lumican (zeige LUM Antikörper) and versican protein expression are associated with colorectal adenoma-to-carcinoma progression
Removal or knockdown of versican may be a possible therapeutic strategy for increasing deposition of insoluble elastin (zeige ELN Antikörper) and stimulating repair of elastic fibers in COPD (zeige ARCN1 Antikörper) lung.
human myeloma tumors displaying CD8 (zeige CD8A Antikörper)(+) infiltration/aggregates underwent VCAN proteolysis at a site predicted to generate a glycosaminoglycan-bereft N-terminal fragment.
versican decreases in follicular dermal papilla as an aging-associated change of human hair follicles
Data indicate that serum versican levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (zeige ADAMTS1 Antikörper) (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican levels were significantly and positively correlated with each other.
the G1 domain of versican can regulate the organization of pericellular hyaluronan and affect phenotype of cultured human dermal fibroblasts
Targeting the hyaluronan and versican content of provisional matrices in a variety of diseases including cancer is becoming an attractive strategy for intervention. (Review)
Versican is produced by Trif (zeige RNF138 Antikörper)- and type I interferon (zeige IFNA Antikörper)-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
Loss of Versican is associated with reduced Lung Inflammatory Response.
Results highlight an important role for versican in regulating the expression and assembly of elastin (zeige ELN Antikörper) and the phenotype of leiomyosarcoma cells.
Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.
Pelvic irradiation increases versican expression in bladder and rectum.
Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.
The data suggest that versican plays an important role in fundamental, overlapping cellular processes in lung development and infection.
Our results show that versican released from glioma promotes tumor expansion through glioma-associated microglial/macrophage TLR2 signaling and subsequent expression of MT1-MMP (zeige MMP14 Antikörper).
Arylsulfatase B (zeige ARSB Antikörper) regulates versican expression by galectin-3 (zeige LGALS3 Antikörper) and AP-1 (zeige JUN Antikörper) mediated transcriptional effects.
The relationship between hyaluronan synthesis and levels of versican, fibronectin (zeige FN1 Antikörper) and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.
chondroitin sulfate proteoglycan 2a
, chondroitin sulfate proteoglycan 2 (versican)
, chondroitin sulfate proteoglycan core protein 2
, glial hyaluronate-binding protein
, large fibroblast proteoglycan
, versican core protein
, chondroitin sulfate proteoglycan 2
, chondroitin sulfate proteoglycan 2b
, versican proteoglycan
, PG-M core protein
, Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M)
, heart defect
, versican core protein-like