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associations, near SPOCK3 were identified and other putative modulators of memory performance were revealed by a
The results of this study suggest that SPOCK3 may modify the genetic risk for Attention-deficit/hyperactivity disorder and personality disorders
High expression of testican 3 is associated with adult T-cell leukemia.
these results demonstrate that Spock3 plays an important role in the formation or maintenance of major neuronal structures in the brain.
The expression of testican-3 in adult mice is restricted to the brain and located diffusely within the extracellular matrix.
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3