anti-Kaninchen Fucosidase, alpha-L- 1, Tissue Antikörper für Western Blotting

Recommended Fucosidase, alpha-L- 1, Tissue Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fucosidase, alpha-L- 1, Tissue (FUCA1) Antikörper
  • FUCA
  • FUCA1
  • 0610006A03Rik
  • 9530055J05Rik
  • Afuc
  • Fuca
  • fuca
  • fuca1
  • ATFUC1
  • F24D13.11
  • F24D13_11
  • alpha-L-fucosidase 1
  • alpha-L-fucosidase 1
  • fucosidase, alpha-L- 1, tissue
  • alpha-L-fucosidase 1 L homeolog
  • FUCA1
  • Fuca1
  • fuca1.L
  • fuca1
  • FUC1
  • LOC9317020
  • LOC100285202
Epitop
N-Term
8
5
5
5
4
4
4
3
3
3
3
3
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
65
31
28
12
3
3
2
2
2
1
1
1
Wirt
Kaninchen
69
14
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
65
36
18
13
9
6
5
5
4
3
3
3
3
3
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2785639
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.283734 ABIN2785640 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN322060 WB Rabbit IgG AA 146-195 Anmelden zum Anzeigen Polyclonal 0
1 ABIN477635 WB Rabbit IgG AA 143-192 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Fucosidase, alpha-L- 1, Tissue (FUCA1) Antikörper
Epitop N-Term
(8), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
(65), (31), (28), (12), (3), (3), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(69), (14), (1)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(7), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(65), (36), (18), (13), (9), (6), (5), (5), (4), (3), (3), (3), (3), (3)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977137.
Sequenz PSPVSWNWNS KDVGPHRDLV GELGTALRKR NIRYGLYHSL LEWFHPLYLL
Homologie Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against FUCA1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human FUCA1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung FUCA1 (FUCA1 Antibody Abstract)
Hintergrund Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis, and that in plasma, FUCA2. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form, coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form, and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FUCA
Protein Interaction Partner: PAXIP1, BARD1, APP, CUL3, VAV2, USP21, MARK2,
Protein Size: 466
Molekulargewicht 54 kDa
Gen-ID 2517
NCBI Accession NM_000147, NP_000138
UniProt P04066
Pathways Glycosaminoglycan Metabolic Process

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 466 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Venditti, Donigan, Bean: "Crypticity and functional distribution of the membrane associated alpha-L-fucosidase of human sperm." in: Molecular reproduction and development, Vol. 74, Issue 6, pp. 758-66, 2007

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Fucosidase, alpha-L- 1, Tissue (FUCA1) (N-Term) antibody (ABIN2785639) WB Suggested Anti-FUCA1 Antibody Titration: 0.2-1 ug/ml
Positive Control...