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Human Polyclonal TSPYL2 Primary Antibody für WB - ABIN1881953
Chai, Sarcevic, Mawson, Toh: SET-related cell division autoantigen-1 (CDA1) arrests cell growth. in The Journal of biological chemistry 2001
Show all 5 Pubmed References
Human Polyclonal TSPYL2 Primary Antibody für ELISA, IHC - ABIN4298777
Kandalaft, Zudaire, Portal-Núñez, Cuttitta, Jakowlew: Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis. in Carcinogenesis 2008
TSPY and TSPX exert opposing effects on the transactivation functions of AR and AR-Vs important for various physiological and disease processes sensitive to male sex hormone actions, thereby not only affecting the pathogenesis of male-specific prostate cancer but also likely contributing to sex differences in the health and diseases of man.
the extent of the duplicated regions in each case encompassing a minimum of three known disease genes TSPYL2, KDM5C (zeige KDM5C Antikörper) and IQSEC2 (zeige IQSEC2 Antikörper), is reported.
homozygous Asp3779Asn and a hemizygous Ile262Met mutations in the LRP2 (zeige LRP2 Antikörper) and TSPYL2 genes, respectively, in a Pakistani family with two boys affected with mild nonsyndromic intellectual disability
Authors demonstrate that human coilin-interacting nuclear ATPase protein (hCINAP) is a novel negative regulator in NF-kappaB (zeige NFKB1 Antikörper) signaling by deactivating IkappaB kinase (zeige CHUK Antikörper) (IKK (zeige CHUK Antikörper)) complex.
TSPYL2 is an essential component of the REST/NRSF (zeige REST Antikörper) transcriptional complex for TGFbeta (zeige TGFB1 Antikörper) signaling activation
The oncogenic events leading to an ectopic activation of TSPY and/or inactivating mutation/epigenetic silencing of TSPX could collectively contribute to the sexual dimorphism(s) in HCC (zeige FAM126A Antikörper) and related liver cancers in male-biased manners.
More importantly, RPS14 (zeige RPS14 Antikörper) was specifically modified with NEDD8 (zeige NEDD8 Antikörper) and hCINAP inhibited RPS14 (zeige RPS14 Antikörper) NEDDylation by recruiting NEDD8-specific protease 1 (zeige SENP8 Antikörper)
TSPX is principally expressed in Sertoli cells in the human testis.
knockdown of CINAP expression results in marked reduction of histone transcription, lower levels of U small nuclear RNAs (U1, U2, U4, and U5), and a loss of cell viability
Overexpression of cell division autoantigen-1 (CDA1) slowed parasite growth and induced expression of bradyzoite-specific proteins. Results showed that changes in host cell transcription can influence the molecular environment for bradyzoite development.
These findings suggest that disrupting Tspyl2 gene expression leads to behavioral and brain morphological alterations that mirror a number of neurodevelopmental psychiatric traits.
Following infection with T. gondii, myotubes but not myoblasts or fibroblasts further upregulate the negative cell cycle regulator (zeige CDKN2A Antikörper) Tspyl2.
We conclude that TSPYL2 contributes to cognitive variability through regulating the expression of Grin2a (zeige GRIN2A Antikörper) and Grin2b (zeige GRIN2B Antikörper).
CDA1 deletion reduces but does not block renal TGF-beta (zeige TGFB1 Antikörper) signaling.
TSPYL2 serves a biological role in maintaining the G1 checkpoint under stress condition.
DENTT may play a role in development of the endocrine tissues, nervous system, lung, oocytes, and thecal cells, and testis [DENTT]
DENTT may play multiple roles in modulating transcriptional responses suggesting new roles for the TTSN superfamily during embryogenesis and differentiation.
Mice treated with hypertonic saline expressed higher CINAP protein levels in the PVN, supporting a role of CINAP in neural response in vivo.
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth.
CASK-interacting nucleosome assembly protein
, CTCL tumor antigen se20-4
, CTCL-associated antigen se20-4
, TSPY-like protein 2
, cell division autoantigen 1
, cutaneous T-cell lymphoma-associated antigen se20-4
, cutaneous T-cell lymphoma-associated tumor antigen se20-4
, differentially expressed nucleolar TGF-beta1 target
, differentially-expressed nucleolar TGF-beta1 target protein
, nuclear protein of 79 kDa
, testis-specific Y-encoded-like protein 2
, testis-specific protein Y encoded-like 2
, TSPY-like 2
, CASK interacting nucleosome assembly protein
, cell division autoantigen 1 nucleolar protein
, nucleolar TGF-beta1 target protein
, Differentially-expressed nucleolar TGF-beta1 target protein