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anti-Human Mesothelin Antikörper:
anti-Mouse (Murine) Mesothelin Antikörper:
anti-Rat (Rattus) Mesothelin Antikörper:
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Human Monoclonal Mesothelin Primary Antibody für FACS - ABIN4897254
Cherkassky, Morello, Villena-Vargas, Feng, Dimitrov, Jones, Sadelain, Adusumilli: Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. in The Journal of clinical investigation 2016
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Chimpanzee Polyclonal Mesothelin Primary Antibody für ELISA, IF - ABIN1583503
Rinkevich, Mori, Sahoo, Xu, Bermingham, Weissman: Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. in Nature cell biology 2013
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Human Monoclonal Mesothelin Primary Antibody für IHC (p), IHC - ABIN259911
Ho, Bera, Willingham, Onda, Hassan, FitzGerald, Pastan: Mesothelin expression in human lung cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2007
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Human Polyclonal Mesothelin Primary Antibody für IHC, IHC (p) - ABIN4333902
Feng, Zhang, Anver, Hassan, Ho: In vivo imaging of human malignant mesothelioma grown orthotopically in the peritoneal cavity of nude mice. in Journal of Cancer 2011
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Human Polyclonal Mesothelin Primary Antibody für ELISA, WB - ABIN4333900
Cheng, Huang, Chang, Hu, Chiang, Chen, Hsieh, Chen: High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma. in British journal of cancer 2009
Human Monoclonal Mesothelin Primary Antibody für FACS - ABIN4897250
Servais, Suzuki, Colovos, Rodriguez, Sima, Fleisher, Rusch, Sadelain, Adusumilli: An in vivo platform for tumor biomarker assessment. in PLoS ONE 2011
Human Monoclonal Mesothelin Primary Antibody für FACS - ABIN4897252
Takenouchi, Hirai, Sakuragi, Yagita, Hamada, Kato: Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Human Monoclonal Mesothelin Primary Antibody für IHC, WB - ABIN233753
Xiang, Phung, Feng, Nagashima, Zhang, Broaddus, Hassan, Fitzgerald, Ho: The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy. in PLoS ONE 2011
Mesothelin-targeted immunotoxin RG7787 increases pancreatic cancer cell sensitivity to taxane-mediated killing by increasing taxane-mediated microtubule stability and priming cells for apoptosis by decreasing levels of the pro-survival factor Mcl-1 (zeige MCL1 Antikörper).
RG7787 plus nab-paclitaxel is very active against primary human mesothelioma cells in vitro as well as in vivo, with serum mesothelin levels correlating with tumor response. These results indicate that this combination could be useful for treating patients with mesothelioma
Efficient growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells.
Mesothelin/mucin 16 (zeige MUC16 Antikörper) signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.(
MiR (zeige MLXIP Antikörper)-21-5p is suggested as novel regulator of MSLN with a possible functional role in cellular growth.
we report herein that high tumor mesothelin expression predicts a shorter PFS and OS in EOC patients and demonstrates that serum mesothelin predicts local tumor mesothelin expression.
We provide new evidence for the role of MSLN in EMT (zeige ITK Antikörper) regulation, tumorigenesis and metastasis. Knockdown of MSLN led to mesenchymal to epithelial transition and less aggressive behavior of lung carcinoma and mesothelioma cells.
MSLN expression increases cell migration and invasion in vitro.
SMRP (zeige ABCC5 Antikörper) but not FBLN3 (zeige FBLN3 Antikörper) has a role in pleural effusions in in malignant pleural mesothelioma
High mesothelin expression is associated with malignant pleural mesothelioma.
Study demonstrates that selective activation of G protein-coupled estrogen receptor (zeige ESR1 Antikörper) can control microglial activation induced by an inflammatory stimulus in vitro, and promote neuronal and functional protection of DA neurons against a unilateral intranigral injection of LPS (zeige TLR4 Antikörper) in male mice.neuroinflammatory diseases.
our findings show that Sulf-1 (zeige SULF1 Antikörper) is an important tumor suppressor gene in hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)), and its over expression downregulates Msln and results in a decrease in HCC (zeige FAM126A Antikörper) cell proliferation, migration, invasion, and lymphatic metastasis.
it suppresses lipopolysaccharide-induced interleukin 6 (zeige IL6 Antikörper) via inhibition of nuclear factor-kappa B pathway in murine macrophage cells
this study revealed a role for GPER (zeige GPER Antikörper) activity in regulating Nox1 (zeige NOX1 Antikörper) abundance and associated O2(-)-mediated structural and functional damage that contributes to disease pathology
These findings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation via its GPER (zeige GPER Antikörper) receptor; thus, antagonism of GPER (zeige GPER Antikörper) represents a potential new target for treatment to reduce metastatic spread.
GPER (zeige GPER Antikörper) protects against hepatic tumorigenesis by regulating inflammatory responses.
Data suggest that prenatal exposure to p,p'-DDT (zeige DDT Antikörper) (an endocrine disrupting pesticide) causes sex- and age-independent attenuation of Gper1 in brain which appears to play key role in propagation of DDT (zeige DDT Antikörper)-induced depressive-like neurotoxicity.
Study suggested that the neuroprotective effect of estrogen requires intact GPER1-associated signaling in an in vitro model of ischemia. The membrane-associated signaling mediates the estrogen actions, and depends on PI3K/Akt (zeige AKT1 Antikörper) signaling for Ask1 (zeige MAP3K5 Antikörper) inhibition that prevents the cell death triggered by ischemia. These mechanisms may help for a therapeutic strategy to target on GPER1 for the treatment of neurological disorders.
Phosphorylation of myosin regulatory light chain triggered by E2 was found to be mediated by estrogen receptor-beta (zeige ESR2 Antikörper) and the G protein-coupled estrogen receptor (zeige ESR1 Antikörper).
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
, megakaryocyte potentiating factor
, pre-pro-megakaryocyte-potentiating factor
, soluble MPF mesothelin related protein
, G protein-coupled receptor 30
, G-protein coupled estrogen receptor 1
, G-protein coupled receptor 30
, chemoattractant receptor-like 2
, constitutively expressed peptide-like receptor like
, membrane estrogen receptor
, protein expressed in renal carcinoma