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GMNN Antigen Profile
Beschreibung des Gens
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Alternative names and synonyms associated with GMNN
geminin, DNA replication inhibitor (GMNN) ELISA Kit
CG3183 gene product from transcript CG3183-RA (geminin) ELISA Kit
geminin, DNA replication inhibitor (gmnn) ELISA Kit
geminin (LOC410093) ELISA Kit
GE24654 gene product from transcript GE24654-RA (Dyak\geminin) ELISA Kit
geminin (Gmnn) ELISA Kit
geminin, DNA replication inhibitor (Gmnn) ELISA Kit