anti-Maus APP Antikörper für Western Blotting

Recommended APP Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Amyloid beta (A4) Precursor Protein (APP) Antikörper
  • AAA
  • ABETA
  • ABPP
  • AD1
  • APPI
  • CTFgamma
  • CVAP
  • PN-II
  • PN2
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • APP-like
  • APPL
  • Abeta
  • BcDNA:GH04413
  • CG7727
  • Dmel\\CG7727
  • EG:65F1.5
  • appl
  • Abpp
  • Adap
  • Ag
  • Cvap
  • E030013M08Rik
  • betaApp
  • app
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740
  • amyloid beta precursor protein
  • amyloid beta (A4) precursor protein
  • beta amyloid protein precursor-like
  • amyloid beta (A4) precursor protein a
  • amyloid beta precursor protein L homeolog
  • APP
  • app
  • Appl
  • App
  • appa
  • app.L
Epitop
AA 672-713, C-Term
105
102
70
39
37
32
31
19
17
15
15
14
14
13
12
10
9
7
7
7
7
6
6
6
5
5
5
5
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
931
383
361
40
27
22
19
18
15
13
12
10
7
7
4
4
4
3
2
2
1
Wirt
Kaninchen
646
261
51
7
2
Klonalität
Polyklonal
Konjugat
Dieser APP Antikörper ist unkonjugiert
51
43
41
17
16
14
14
14
13
13
13
13
13
13
13
8
8
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
668
405
293
159
158
122
82
57
40
36
17
15
15
10
8
3
3
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN3043787
$ 280.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2563753 ABIN2777738 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.2563753 ABIN2777739 IHC WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.2563753 ABIN2787850 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN2779739 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN2855011 ICC IF IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN2465038 ELISA WB Goat N-Term Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN358841 EIA WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 5
3.2563753 ABIN1449275 WB Mouse IgG1 AA 18-38 Anmelden zum Anzeigen 3-00E-009 3
3.2563753 ABIN2464967 ELISA WB Goat N-Term Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN4281249 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
3.2563753 ABIN1871049 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN1532190 IF IHC ELISA WB Rabbit IgG AA 711-760 Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN1531173 IF IHC ELISA WB Rabbit IgG AA 711-760, pThr743 Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN317496 EIA IHC (p) WB Mouse IgG2b AA 18-289 Anmelden zum Anzeigen J4H9 0
3.2563753 ABIN2451920 IC IF IHC WB Rabbit C-Term, AA 671-695 Anmelden zum Anzeigen Polyclonal 5
3.2563753 ABIN1869978 IHC WB Rabbit IgG pThr743 Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN2451919 IC IF WB Rabbit N-Term, AA 18-38 Anmelden zum Anzeigen Polyclonal 4
3.2563753 ABIN1869980 WB Rabbit IgG pThr668 Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN1871051 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.2563753 ABIN1858064 ICC IHC WB Rabbit IgG AA 672-770 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Amyloid beta (A4) Precursor Protein (APP) Antikörper
Epitop AA 672-713, C-Term
(105), (102), (70), (39), (37), (32), (31), (19), (17), (15), (15), (14), (14), (13), (12), (10), (9), (7), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(931), (383), (361), (40), (27), (22), (19), (18), (15), (13), (12), (10), (7), (7), (4), (4), (4), (3), (2), (2), (1)
Wirt Kaninchen
(646), (261), (51), (7), (2)
Klonalität
Polyklonal
Konjugat Dieser APP Antikörper ist unkonjugiert
(51), (43), (41), (17), (16), (14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(668), (405), (293), (159), (158), (122), (82), (57), (40), (36), (17), (15), (15), (10), (8), (3), (3), (2), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-APP Antikörper

Target Details APP Anwendungsinformationen Handhabung Referenzen für anti-APP Antikörper (ABIN3043787) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Sequenz DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: amyloid beta (A4) precursor protein
Protein Name: Amyloid beta A4 protein
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human APP(672-713aa DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA), different from the related mouse and rat sequences by three amino acids.
Isotyp IgG

Target Details APP

Produktdetails anti-APP Antikörper Anwendungsinformationen Handhabung Referenzen für anti-APP Antikörper (ABIN3043787) Bilder zurück nach oben
Antigen
Andere Bezeichnung APP (APP Antibody Abstract)
Hintergrund Beta Amyloid, also called Abeta or Abeta, denotes peptides of 36-43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

Synonyms: A4 antibody|A4 antibody|A4_HUMAN antibody|AAA antibody|AAA antibody|ABETA antibody|ABETA antibody|ABPP antibody|ABPP antibody|AD1 antibody|AICD-50 antibody|AICD-57 antibody|AICD-59 antibody|AID(50) antibody|AID(57) antibody|AID(59) antibody|Alzheimer disease amyloid protein antibody|Alzheimers Disease Amyloid Protein antibody|Amyloid B antibody|amyloid beta (A4) precursor protein antibody|amyloid beta A4 protein antibody|Amyloid Beta A4 Protein Precursor antibody|Amyloid Beta antibody|Amyloid intracellular domain 50 antibody|Amyloid intracellular domain 57 antibody|Amyloid intracellular domain 59 antibody|Amyloid of Aging and Alzheimer Disease antibody|APP antibody|APPI antibody|APPI antibody|B Amyloid antibody|Beta APP antibody|beta-amyloid peptide antibody|Beta-APP40 antibody|Beta-APP42 antibody|C31 antibody|Cerebral Vascular Amyloid Peptide antibody|CTFgamma antibody|CVAP antibody|CVAP antibody|Gamma-CTF(50)antibody|Gamma-CTF(57) antibody|Gamma-CTF(59) antibody|peptidase nexin-II antibody|PN II antibody|PN-II antibody|PN2 antibody|PreA4 antibody|PreA4 antibody|Protease nexin II antibody|Protease nexin-II antibody|S-APP-alpha antibody|S-APP-beta antibody
Gen-ID 351
UniProt P05067
Pathways Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

Anwendungsinformationen

Produktdetails anti-APP Antikörper Target Details APP Handhabung Referenzen für anti-APP Antikörper (ABIN3043787) Bilder zurück nach oben
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for APP is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-APP Antikörper Target Details APP Anwendungsinformationen Referenzen für anti-APP Antikörper (ABIN3043787) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-APP Antikörper (ABIN3043787)

Produktdetails anti-APP Antikörper Target Details APP Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Sun, Zhou, Yi, Jiang, Yuan: "Lead-induced morphological changes and amyloid precursor protein accumulation in adult rat hippocampus." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 513-7, 2014

Qin, Yao, Huang: "Effects of compound danshen tablets on spatial cognition and expression of brain beta-amyloid precursor protein in a rat model of Alzheimer's disease." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine, Vol. 32, Issue 1, pp. 63-6, 2012

Li, Li, Huang, Kan, Wang, Wu, Yin, Yao: "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." in: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, 2011

Nie, Luo, Huang, Gong, Wu, Shi: "Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus." in: European journal of pharmacology, Vol. 626, Issue 2-3, pp. 213-8, 2009

Bilder

Produktdetails anti-APP Antikörper Target Details APP Anwendungsinformationen Handhabung Referenzen für anti-APP Antikörper (ABIN3043787) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Mouse Brain Tissue
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Rat Brain Tissue
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml WB: R...
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml Lane ...