anti-Ratte (Rattus) PMS2 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended PMS2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) Antikörper
  • HNPCC4
  • PMS2CL
  • PMSL2
  • AW555130
  • Pmsl2
  • PMS1 homolog 2, mismatch repair system component
  • PMS1 homolog2, mismatch repair system component
  • mismatch repair endonuclease PMS2
  • PMS2
  • Pms2
  • LOC463257
  • LOC107984056
Reaktivität
Human, Maus, Ratte (Rattus)
123
41
18
2
2
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
69
53
1
Klonalität
Polyklonal
Konjugat
Dieser PMS2 Antikörper ist unkonjugiert
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
95
54
53
34
26
19
10
9
3
2
2
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Produktnummer ABIN127133
$ 346.50
Zzgl. Versandkosten $45.00

General

Antigen PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(123), (41), (18), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(69), (53), (1)
Klonalität
Polyklonal
Konjugat Dieser PMS2 Antikörper ist unkonjugiert
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(95), (54), (53), (34), (26), (19), (10), (9), (3), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PMS2 Antikörper

Target Details PMS2 Anwendungsinformationen Handhabung Bilder
Spezifität The antibody recognizes ~100 kDa PMS2.
Reinigung Peptide Affinity Chromatography.
Immunogen Synthetic peptide surrounding amino acid 846 of human PMS2
Plasmids, Primers & others

Target Details PMS2

Produktdetails anti-PMS2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung PMS2 (PMS2 Antibody Abstract)
Hintergrund Inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were initially demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 - 45 % of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Two additional homologs of the prokaryotic MutL gene, designated PMS1 and PMS2, have been identified and shown to be mutated in the germline of HNPCC patients.Synonyms: DNA mismatch repair protein PMS2, Mismatch repair endonuclease PMS2, PMS1 protein homolog 2, PMSL2
Gen-ID 5395
NCBI Accession NP_000526
UniProt P54278
Pathways DNA Reparatur, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-PMS2 Antikörper Target Details PMS2 Handhabung Bilder zurück nach oben
Applikations-hinweise Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PMS2 Antikörper Target Details PMS2 Anwendungsinformationen Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer PBS containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal.
Konservierungs-mittel Thimerosal (Merthiolate)
Vorsichtsmaßnahmen This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung -20 °C/-80 °C
Informationen zur Lagerung Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.