anti-Kaninchen TFAM Antikörper für Western Blotting

Recommended TFAM Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Transcription Factor A, Mitochondrial (TFAM) Antikörper
  • tcf6
  • mttf1
  • mttfa
  • tcf6l1
  • tcf6l2
  • tcf6l3
  • mttfa-A
  • xl-mtTFA
  • MGC153358
  • zgc:153358
  • MTTF1
  • MTTFA
  • TCF6
  • TCF6L1
  • TCF6L2
  • TCF6L3
  • AI661103
  • Hmgts
  • mtTFA
  • tsHMG
  • Mttfa
  • transcription factor A, mitochondrial
  • transcription factor A, mitochondrial L homeolog
  • TFAM
  • tfam.L
  • tfam
  • Tfam
Epitop
N-Term
18
12
9
6
6
6
6
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen
115
55
41
4
2
1
1
Wirt
Kaninchen
121
21
Klonalität
Polyklonal
Konjugat
Dieser TFAM Antikörper ist unkonjugiert
7
7
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
113
72
60
45
43
36
20
13
7
7
4
3
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2777277
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2594213 ABIN2779902 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.2594213 ABIN2779903 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN214152 IHC (p) WB Rabbit IgG AA 75-124 Anmelden zum Anzeigen Polyclonal 0
1 ABIN216782 IHC (p) WB Rabbit IgG AA 169-218 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Transcription Factor A, Mitochondrial (TFAM) Antikörper
Epitop N-Term
(18), (12), (9), (6), (6), (6), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen
(115), (55), (41), (4), (2), (1), (1)
Wirt Kaninchen
(121), (21)
Klonalität
Polyklonal
Konjugat Dieser TFAM Antikörper ist unkonjugiert
(7), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(113), (72), (60), (45), (43), (36), (20), (13), (7), (7), (4), (3), (2), (2)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TFAM Antikörper

Target Details TFAM Anwendungsinformationen Handhabung Referenzen für anti-TFAM Antikörper (ABIN2777277) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984969.
Sequenz AKTTELIRRI AQRWRELPDS KKKIYQDAYR AEWQVYKEEI SRFKEQLTPS
Homologie Cow: 92%, Dog: 83%, Guinea Pig: 75%, Horse: 92%, Human: 100%, Mouse: 75%, Pig: 92%, Rabbit: 83%
Produktmerkmale This is a rabbit polyclonal antibody against Transcription Factor AntibodiesAM. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TFAM

Target Details TFAM

Produktdetails anti-TFAM Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TFAM Antikörper (ABIN2777277) Bilder zurück nach oben
Antigen
Andere Bezeichnung TFAM (TFAM Antibody Abstract)
Hintergrund The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: TCF6, MtTF1, mtTFA, TCF6L1, TCF6L2, TCF6L3
Protein Interaction Partner: AGTRAP, FBXW11, ARL6IP1, NEDD1, PPP2R1A, GRSF1, UBC, MDM2, SUZ12, EED, PAN2, MYC, FN1, C1QBP, CAND1, COPS5, CUL3, ELAVL1, ICT1, TFB2M, TFB1M, PNP, NRF1,
Protein Size: 246
Molekulargewicht 29 kDa
Gen-ID 7019
NCBI Accession NM_003201, NP_003192
UniProt Q00059
Pathways Chromatin Binding

Anwendungsinformationen

Produktdetails anti-TFAM Antikörper Target Details TFAM Handhabung Referenzen für anti-TFAM Antikörper (ABIN2777277) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 246 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TFAM Antikörper Target Details TFAM Anwendungsinformationen Referenzen für anti-TFAM Antikörper (ABIN2777277) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TFAM Antikörper (ABIN2777277)

Produktdetails anti-TFAM Antikörper Target Details TFAM Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ogasawara, Liu, Pelicano, Hammoudi, Croce, Keating, Huang: "Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53." in: Mitochondrion, Vol. 31, pp. 33-39, 2016

Kemper, Stirone, Krause, Duckles, Procaccio: "Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection." in: European journal of pharmacology, Vol. 723, pp. 322-9, 2014

Vettor, Valerio, Ragni, Trevellin, Granzotto, Olivieri, Tedesco, Ruocco, Fossati, Fabris, Serra, Carruba, Nisoli: "Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism." in: American journal of physiology. Endocrinology and metabolism, Vol. 306, Issue 5, pp. E519-28, 2014

Kemper, Zhao, Duckles, Krause: "Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 1, pp. 122-8, 2013

Teodoro, Duarte, Gomes, Varela, Peixoto, Rolo, Palmeira: "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." in: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, 2013

Miyazaki, Iwasawa, Nakashima, Mori, Shigemoto, Nakamura, Katagiri, Takayanagi, Tanaka: "Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption." in: The Journal of biological chemistry, Vol. 287, Issue 45, pp. 37808-23, 2012

Lu, Chen, Zhang, Wang, Luo, Huang: "ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction." in: Cell death & disease, Vol. 3, pp. e422, 2012

Walters, Wallace: "Urea cycle gene expression is suppressed by PFOA treatment in rats." in: Toxicology letters, Vol. 197, Issue 1, pp. 46-50, 2010

Walters, Bjork, Wallace: "Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats." in: Toxicology, Vol. 264, Issue 1-2, pp. 10-5, 2009

Shi, Burkart, Nicoloro, Czech, Straubhaar, Corvera: "Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells." in: The Journal of biological chemistry, Vol. 283, Issue 45, pp. 30658-67, 2008

Bilder

Produktdetails anti-TFAM Antikörper Target Details TFAM Anwendungsinformationen Handhabung Referenzen für anti-TFAM Antikörper (ABIN2777277) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (Image 2)