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anti-Human BRD3 Antikörper:
anti-Mouse (Murine) BRD3 Antikörper:
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Human Polyclonal BRD3 Primary Antibody für ChIPSeq, ChIP - ABIN2668232
Sartor, Powell, Brothers, Wahlestedt: Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2015
Human Polyclonal BRD3 Primary Antibody für IHC (p), WB - ABIN392610
Klein, Kabala, Grabiec, Gay, Kolling, Lin, Gay, Tak, Prinjha, Ospelt, Reedquist: The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts. in Annals of the rheumatic diseases 2014
conclude that BRD3/4 and the FLT3 (zeige FLT3 Antikörper)-TAK1 (zeige MAP3K7 Antikörper)/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells
The bromodomain and extraterminal domain (BET) family consists of BRDT (zeige BRDT Antikörper), BRD2 (zeige BRD2 Antikörper), BRD3, and BRD4 (zeige BRD4 Antikörper), each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites.
Ewing sarcoma may be susceptible to treatment with epigenetic inhibitors blocking BRD3/4 activity and the associated pathognomonic EWS (zeige EWSR1 Antikörper)-FLT1 (zeige FLT1 Antikörper) transcriptional program.
An isoform of BRD3, BRD3R (BRD3 with Reprogramming activity) is a reprogramming factor.
Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function.
BRD2 (zeige BRD2 Antikörper), BRD3, and BRD4 (zeige BRD4 Antikörper) interact with gammaretroviral INs (zeige INS Antikörper) and serve as cofactors for murine leukemia virus integration.
The BRDT (zeige BRDT Antikörper) gene was not expressed in testicular tissue from patients with Sertoli cells only, whereas the other three genes of the BET family retained expression in all the sperm pathologies.
the structural basis for GATA1 (zeige GATA1 Antikörper) and Brd3 interaction was described.
BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation.
Results report that the double bromodomain proteins Brd2 (zeige BRD2 Antikörper) and Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of transcribed genes.
Brd3 knockout significantly decreased the recruitment of acetylase CBP (zeige CREBBP Antikörper) to IL6 (zeige IL6 Antikörper) gene promoter, and the acetylation level of histone3 within IL6 (zeige IL6 Antikörper) gene promoter was repressed.
Data show that infection of macrophages with Listeria monocytogenes caused binding of the BET proteins Brd2, Brd3, and, most prominently, Brd4 to the Nos2 promoter.
Brd3 associates with acetylated GATA1 (zeige GATA1 Antikörper) to promote its chromatin occupancy at erythroid target genes
A conserved but uncharacterized gene encoding Brd3, which was down-regulated during endothelial differentiation, was identified.
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.
bromodomain containing 3
, bromodomain containing protein 3
, bromodomain-containing protein 3-like
, RING3-like protein
, bromodomain-containing 3
, bromodomain-containing protein 3
, bromodomain-containing FSH-like protein FSRG2