anti-Meerschweinchen Sphingomyelin Synthase 1 Antikörper für Western Blotting

Recommended Sphingomyelin Synthase 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Sphingomyelin Synthase 1 (SGMS1) Antikörper
  • MGC81436
  • TMEM23
  • MOB
  • MOB1
  • SMS1
  • hmob33
  • 9530058O11Rik
  • AI841905
  • C80702
  • Mob
  • Sms1
  • Sor1
  • Tmem23
  • sphingomyelin synthase 1
  • sphingomyelin synthase 1 S homeolog
  • phosphatidylcholine:ceramide cholinephosphotransferase 1
  • SGMS1
  • sgms1.S
  • LOC100013212
  • Sgms1
Epitop
Middle Region
15
11
10
8
2
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
55
31
25
3
3
3
3
3
2
2
2
1
Wirt
Kaninchen
55
Klonalität
Polyklonal
Konjugat
Dieser Sphingomyelin Synthase 1 Antikörper ist unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
40
20
20
13
8
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2786225
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2563753 ABIN2774110 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN463985 WB Rabbit IgG AA 144-193 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1104254 WB Rabbit AA 154-203 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Sphingomyelin Synthase 1 (SGMS1) Antikörper
Epitop Middle Region
(15), (11), (10), (8), (2), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(55), (31), (25), (3), (3), (3), (3), (3), (2), (2), (2), (1)
Wirt Kaninchen
(55)
Klonalität
Polyklonal
Konjugat Dieser Sphingomyelin Synthase 1 Antikörper ist unkonjugiert
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(40), (20), (20), (13), (8), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper

Target Details Sphingomyelin Synthase 1 Anwendungsinformationen Handhabung Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN1541177.
Sequenz LTTVMISVVH ERVPPKEVQP PLPDTFFDHF NRVQWAFSIC EINGMILVGL
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
Produktmerkmale This is a rabbit polyclonal antibody against Sgms1. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of Mouse Sgms1

Target Details Sphingomyelin Synthase 1

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225) Bilder zurück nach oben
Antigen
Andere Bezeichnung Sgms1 (SGMS1 Antibody Abstract)
Hintergrund Bidirectional lipid cholinephosphotransferase is capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Sgms1 directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Sgms1 does not function strictly as a SM synthase and suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sgms1 may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Alias Symbols: 9530058O11Rik, AI841905, C80702, MGC30540, Mob, Sms1, Sor1, Tmem23
Protein Size: 419
Molekulargewicht 46 kDa
Gen-ID 208449
NCBI Accession NM_144792, NP_659041
UniProt Q8VCQ6
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper Target Details Sphingomyelin Synthase 1 Handhabung Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 419 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper Target Details Sphingomyelin Synthase 1 Anwendungsinformationen Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225)

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper Target Details Sphingomyelin Synthase 1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Miyamoto, Hsu, Hamm, Darshi, Diamond-Stanic, Declèves, Slater, Pennathur, Stauber, Dorrestein, Sharma: "Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator." in: EBioMedicine, Vol. 7, pp. 121-34, 2016

Bilder

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper Target Details Sphingomyelin Synthase 1 Anwendungsinformationen Handhabung Referenzen für anti-Sphingomyelin Synthase 1 Antikörper (ABIN2786225) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Sphingomyelin Synthase 1 (SGMS1) (Middle Region) antibody (ABIN2786225) WB Suggested Anti-Sgms1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Muscle