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LILRB1 Antigen Profile
Beschreibung des Gens
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names and synonyms associated with LILRB1
leukocyte immunoglobulin like receptor B1 (LILRB1) ELISA Kit
CD85J ELISA Kit
ILT-2 ELISA Kit
ILT2 ELISA Kit
LIR-1 ELISA Kit
LIR1 ELISA Kit
MIR-7 ELISA Kit
MIR7 ELISA Kit
Bezeichner auf Proteinebene für LILRB1
CD85 antigen-like family member J
, Ig-like transcript 2
, leukocyte immunoglobulin-like receptor subfamily B member 1
, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform
, monocyte/macrophage immunoglobulin-like receptor 7