anti-Human CCL5 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended CCL5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Chemokine (C-C Motif) Ligand 5 (CCL5) Antikörper
  • Rantes
  • Scya5
  • D17S136E
  • RANTES
  • SCYA5
  • SIS-delta
  • SISd
  • TCP228
  • eoCP
  • MuRantes
  • C-C motif chemokine 5-like
  • C-C motif chemokine ligand 5
  • chemokine (C-C motif) ligand 5
  • LOC100230935
  • CCL5
  • Ccl5
Epitop
AA 71-89
33
15
7
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Human, Maus
199
106
50
24
14
4
4
3
3
3
1
1
1
1
1
Wirt
Kaninchen
191
84
37
5
3
1
Klonalität
Polyklonal
Konjugat
Dieser CCL5 Antikörper ist unkonjugiert
55
24
14
11
8
6
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
224
183
75
55
37
32
19
15
14
12
7
5
3
3
3
2
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN674949
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN888513 IF (p) Alexa Fluor 488 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN888514 IF (p) Alexa Fluor 555 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN888516 IF (p) Alexa Fluor 350 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN888515 IF (p) Alexa Fluor 647 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN674952 IF (p) Cy3 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN674953 IF (p) Cy5 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN674954 IF (p) Cy5.5 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN674956 IF (p) FITC Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN674955 IF (p) Cy7 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2811265 IF (p) Alexa Fluor 594 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4999352 IF (p) Alexa Fluor 680 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4999353 IF (p) Alexa Fluor 750 Rabbit IgG AA 71-89 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Chemokine (C-C Motif) Ligand 5 (CCL5) Antikörper
Epitop AA 71-89
(33), (15), (7), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Human, Maus
(199), (106), (50), (24), (14), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1)
Wirt Kaninchen
(191), (84), (37), (5), (3), (1)
Klonalität
Polyklonal
Konjugat Dieser CCL5 Antikörper ist unkonjugiert
(55), (24), (14), (11), (8), (6), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(224), (183), (75), (55), (37), (32), (19), (15), (14), (12), (7), (5), (3), (3), (3), (2), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCL5 Antikörper

Target Details CCL5 Anwendungsinformationen Handhabung Referenzen für anti-CCL5 Antikörper (ABIN674949) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CCL5
Isotyp IgG

Target Details CCL5

Produktdetails anti-CCL5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCL5 Antikörper (ABIN674949) Bilder zurück nach oben
Antigen
Andere Bezeichnung Ccl5/Rantes (CCL5 Antibody Abstract)
Hintergrund

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, PubMed:13864, PubMed:8525373, PubMed:9516414, PubMed:15923218). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485).

Subcellular location: Secreted, Helical

Synonyms: SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS-delta, C-C motif chemokine 5, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, T-cell-specific protein RANTES, CCL5

Gen-ID 6352
UniProt P13501
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-CCL5 Antikörper Target Details CCL5 Handhabung Referenzen für anti-CCL5 Antikörper (ABIN674949) Bilder zurück nach oben
Applikationshinweise IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCL5 Antikörper Target Details CCL5 Anwendungsinformationen Referenzen für anti-CCL5 Antikörper (ABIN674949) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-CCL5 Antikörper (ABIN674949)

Produktdetails anti-CCL5 Antikörper Target Details CCL5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Irie, Tomofuji, Ekuni, Fukuhara, Uchida, Kataoka, Kobayashi, Kikuchi, Mitani, Shimazaki, Morita: "Age-related changes of CD4+T cell migration and cytokine expression in germ-free and SPF mice periodontium." in: Archives of oral biology, Vol. 87, pp. 72-78, 2018 Von den Autoren verwendete Methode: Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: bone

Sun, Roberts, Mauerhan, Hanley: "Biological effects and osteoarthritic disease-modifying activity of small molecule CM-01." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Guinea Pig). Weitere Details: Sample: tibial plateau

Hwaiz, Rahman, Syk, Zhang, Thorlacius: "Rac1-dependent secretion of platelet-derived CCL5 regulates neutrophil recruitment via activation of alveolar macrophages in septic lung injury." in: Journal of leukocyte biology, 2015 (Probematerial (Species): Mouse (Murine)).

Herder, Iskandar, Kegler, Hansmann, Elmarabet, Khan, Kalkuhl, Deschl, Baumgärtner, Ulrich, Beineke: "Dynamic Changes of Microglia/Macrophage M1 and M2 Polarization in Theiler's Murine Encephalomyelitis." in: Brain pathology (Zurich, Switzerland), Vol. 25, Issue 6, pp. 712-23, 2015

Pattappa, Peroglio, Sakai, Mochida, Benneker, Alini, Grad: "CCL5/RANTES is a key chemoattractant released by degenerative intervertebral discs in organ culture." in: European cells & materials, Vol. 27, pp. 124-36; discussion 136, 2014 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Cow (Bovine)).

Bilder

Produktdetails anti-CCL5 Antikörper Target Details CCL5 Anwendungsinformationen Handhabung Referenzen für anti-CCL5 Antikörper (ABIN674949) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 71-89) antibody (ABIN674949) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CCL5/RANT...