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Pastori, Pignatelli, Farcomeni, Menichelli, Nocella, Carnevale, Violi: Aging-Related Decline of Glutathione Peroxidase 3 and Risk of Cardiovascular Events in Patients With Atrial Fibrillation. in Journal of the American Heart Association 2016
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Hadzi-Petrushev, Jankulovski, Hristov, Mladenov: L-2-oxothiazolidine-4-carboxylate influence on age- and heat exposure-dependent redox changes in rat's blood plasma. in The journal of physiological sciences : JPS 2011
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Ramos-Mozo, Madrigal-Matute, Martinez-Pinna, Blanco-Colio, Lopez, Camafeita, Meilhac, Michel, Aparicio, Vega de Ceniga, Egido, Martín-Ventura et al.: Proteomic analysis of polymorphonuclear neutrophils identifies catalase as a novel biomarker of abdominal aortic aneurysm: potential implication of oxidative stress in abdominal aortic aneurysm ... in Arteriosclerosis, thrombosis, and vascular biology 2011
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Mapanga, Joseph, Symington, Garson, Kimar, Kelly-Laubscher, Essop: Detrimental effects of acute hyperglycaemia on the rat heart. in Acta physiologica (Oxford, England) 2014
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Mouse (Murine) Catalase ELISA Kit für Sandwich ELISA - ABIN578280
Lv, Deng, Yu, Wang, Gong, Jia, Wang: Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease. in Free radical research 2015
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity.
Transcriptional activation of catalase by the DNA replication-related element (DRE)/DRE (zeige SUFUH ELISA Kits)- binding factor (DREF) system.
SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions
CAT2 role in photorespiration.
CAT2 coordinates salicylic acid repression of auxin accumulation and jasmonic acid biosynthesis in plant defense
All of the study findings suggest that ABI5 regulates seed germination at least partly by affecting ROS (zeige ROS1 ELISA Kits) homeostasis.
The CAT2 promoter is regulated by the ACGT motif (Box2) rather than by the G-Box binding motif (Box1) in the vegetative phase of development.
maintaining higher CAT and POD activities might be one of the reasons that the disruption of AtWNK8 enhances the tolerance to salt stress.
CAT1 (zeige SLC7A1 ELISA Kits) has a role in the resistance to the hemibiotrophic bacterial pathogen Pseudomonas syringae via a constitutively activated salicylic acid (SA) pathway.
CAT2 and NCA1 promote autophagy-dependent cell death in Arabidopsis.
The hyponastic leaves of cat2-1 reveal crosstalk between H2 O2 and auxin signalling that is mediated by changes in glutathione redox status.
NADP-ME2 transcripts accumulated in response to ozone or in mutants undergoing intracellular oxidative stress. Loss of NADP-ME2 function had little effect on cat2-triggered changes in glutathione or NADPH.
The results obtained in this work suggest that variations of H(2)O(2) and catalase expression in Bombyx eggs are involved in diapause initiation and termination
the decrease in accessible surface area and increase in pKa of important lysine residues were considered as predominant factors in decreased glycation of bovine liver catalase by curcumin.
ITC confirms the stability of bovine liver catalase (BLC (zeige CXCL13 ELISA Kits))upon gemini combination. Docking provides support to fluorescence results by presenting the localization site of m-E2-m surfactants near to aromatic residues (mainly Tyr (zeige TYR ELISA Kits), Trp (zeige TRPC5 ELISA Kits) and Phe)
Data show that liver catalase is able to tolerate very high levels of the modifying alpha-oxoaldehyde methylglyoxal so that its essential enzymatic function is not impaired.
The structure of bovine liver catalase determined from a single crystal at 3.2 A resolution by MicroED, is reported.
These maps demonstrate that it is indeed possible to build atomic models from such crystals and even to determine the charged states of amino acid residues in the Ca(2 (zeige CA2 ELISA Kits)+)-binding sites of Ca(2+)-ATPase (zeige CA-P60A ELISA Kits) and that of the iron atom in the heme in catalase.
Data indicate compatible osmolytes, proline, xylitol, and valine destabilize the denatured form of the catalase enzyme and, therefore, increase its disaggregation and thermal stability.
Flavonoid inhibition of catalase activity is, at least partially, due to the formation of hydrogen bonds between catalase and the flavonoid.
Comparison of deoxyferrous and oxyferrous complexes of cAOS and MAP with bovine liver catalase elucidates unresolved mechanistic questions in the catalytic cycles of these enzymes
Catalase is not influenced by the solvent during the catalytic reaction, which represents a lower energy barrier to be crossed in the overall energetics of the reaction, a fact that contributes to the high turnover rate of catalase.
At room temperature (25.0 degrees C) and higher, the addition of high concentrations of polymer is found to significantly enhance the affinity of SOD for catalase.
It has been shown that the AP-1 (zeige FOSB ELISA Kits) family member JunB (zeige JUNB ELISA Kits) and retinoic acid receptor alpha (RARa (zeige RARA ELISA Kits)) mediate catalase transcriptional activation and repression, respectively, by controlling chromatin remodeling through a histone deacetylases-dependent mechanism.
these findings lend credit to the idea that inefficient catalase import, when coupled with the role of PEX5 (zeige PEX5 ELISA Kits) as a redox-regulated import receptor, constitutes a cellular defense mechanism to combat oxidative insults of extra-peroxisomal origin.
our data suggest that gene polymorphisms of GPX1 (zeige GPX1 ELISA Kits) Pro198Leu and CAT C262T may have a protective role in the development of primary open-angle glaucoma in a Polish population.
Mutated obese carries of SOD1 (zeige SOD1 ELISA Kits) -251, SOD2 (zeige SOD2 ELISA Kits) 47 and CAT -262 are associated with a higher distribution of fat in comparison with obese wild-type carriers.
The present study determined that ARE, CLP (zeige CALML3 ELISA Kits), CAT, and MPO (zeige MPO ELISA Kits) levels are different between the pediatric patients with sepsis and healthy controls. ARE level can be a potent biomarker for sepsis in critical patients in intensive care units.
Superoxide dismutase (zeige SOD1 ELISA Kits) and catalase activities were lower in type 1 myotonic dystrophy patients compared to healthy controls
results suggest that, in dyslipidemic patients, the catalase rs1001179 TT genotype is associated with higher HbA1c and plasma triglyceride levels, and that these associations may be modulated by BMI and/or age
The levels of expression of carbonic anhydrase 2 (zeige CA2 ELISA Kits), catalase, and PRDX2 (zeige PRDX2 ELISA Kits) in the nipple discharge were significantly increased in breast ductal carcinoma patients as compared to controls.
Study demonstrates that SOD2 (zeige SOD2 ELISA Kits) rs4880, GPX1 (zeige GPX1 ELISA Kits) rs1050450 and CAT rs1001179 are not associated with an increased susceptibility to epilepsy after neonatal hypoxic-ischemic encephalopathyor its drug resistance
The antioxidative effects of the Mediterranean diet against breast cancer risk may be enhanced by the wild-type alleles of the MnSOD (zeige SOD2 ELISA Kits) or CAT SNPs among Greek-Cypriot women.
Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
Mice devoid of catalase develop an obese, pre-diabetic phenotype and provide compelling evidence for catalase (or its products) being integral in metabolic regulation.
Data indicate that alpha-syntrophin (zeige SNTA1 ELISA Kits) plays an important role in the regulation of oxidative stress from endogenously generated reactive oxygen species (ROS (zeige ROS1 ELISA Kits)) during myoblast differentiation by modulating the protein stability of catalase.
Overexpression of catalase reduced the concentrations of microsomal benzo(a)pyrene phenols and diols/diones by ~45 and 95%, respectively.
Results indicate that mitochondrial catalase likely functions to preclude the formation of high levels of H2O2 without perturbing redox-dependent signaling.
Age strongly interacts with catalase targeted to the mitochondria, consistent with antagonistic pleiotropy in the reverse of the typical direction.
data suggest that catalase is required not only to scavenge reactive oxygen species, but also to protect DNA from oxidative damage during meiotic maturation in mouse oocytes.
catalase protects mouse hearts against diabetic cardiomyopathy, partially by suppressing NF-kappaB (zeige NFKB1 ELISA Kits)-dependent inflammatory responses and associated protein nitration.
Hypoxia-generated red blood cells have low catalase and are preferentially destroyed.
The study shows how maturation of active catalase can be influenced by nitric oxide, S-nitrosylated GAPDH (zeige GAPDH ELISA Kits), and thioredoxin-1 (zeige TXN ELISA Kits), and how maturation may become compromised in inflammatory conditions such as asthma.
fenofibrate almost completely abolished GM-induced reactive oxygen species generation, which seemed to be mediated at least in part by the restoration of the expression of PPARalphadependent antioxidant enzymes, including catalase and superoxide dismutase (SOD)-1 (zeige SOD1 ELISA Kits).
Antioxidants diphenyliodonium and N-acetylcysteine or overexpression of zebrafish catalase in GF-1 (zeige SOS1 ELISA Kits) cells also reduced ROS (zeige ROS1 ELISA Kits) production and protected cells for enhancing host survival rate due to red-spotted grouper nervous necrosis virus infection.
Effect of beta-naphthoflavone on catalase in various brain regions of pig is reported.
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
, cytosolic catalase
, CaTaLase family member (ctl-3)
, catalase 1