TMX1 Proteine (TMX1)

Bezeichnung:: Thioredoxin-Related Transmembrane Protein 1 Proteine (TMX1)

Auf www.antikoerper-online.de finden Sie aktuell 7 Thioredoxin-Related Transmembrane Protein 1 (TMX1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TMX1 Antikörper (60) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 72 TMX1 Produkte verfügbar.

Synonyme:: 2810425A04Rik, AI465319, PDIA11, TMX, TXNDC, Txndc1

alle Proteine anzeigen	Gen	GeneID	UniProt
	TMX1	81542	Q9H3N1
	TMX1	72736	Q8VBT0
Ratte TMX1	TMX1	362751
Weitere Synonyme anzeigen

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Verknüpfte Pathways mit TMX1 Proteine

Cell RedoxHomeostasis

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Weitere Proteine zu TMX1 Interaktionspartnern

Human Thioredoxin-Related Transmembrane Protein 1 (TMX1) Interaktionspartner

TMX1 selectively intervenes in clearance of membrane-tethered Endoplasmic Reticulum-Associated Degradation substrates. TMX1 preferentially acts on membrane-tethered folding-defective polypeptides essentially ignoring the same misfolded ectodomains, when not associated to the Endoplasmic Reticulum membrane.
TMX1 increases mitochondrial ATP production and apoptosis progression.
Here we show that TMX1, one of the few transmembrane members of the family, forms functional complexes with the ER lectin calnexin and preferentially intervenes during maturation of cysteine-containing, membrane-associated proteins
We conclude that TMX plays a major role in host defense under the type of inflammatory conditions associated with oxidative stress.
the silencing of TMX in the prostatic cell line DU145 reduced the sensitivity of the cells to ricin intoxication further confirming a role for this enzyme in intracellular ricin activation.
TMX1 is enriched on the mitochondria-associated membrane. Targeting TMX to the MAM requires palmitoylation of two membrane-proximal cytosolic cysteines.
These results suggest a specific role for transmembrane thioredoxin-related protein TMX and its mechanism of action in redox-based ER quality control.

TMX1 Protein Überblick

Protein Überblick

TXNDC1 is a thioredoxin (TXN\; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001

Alternative names and synonyms associated with TMX1

thioredoxin related transmembrane protein 1 (TMX1)
thioredoxin-related transmembrane protein 1 (Tmx1)

2810425A04Rik Protein
AI465319 Protein
PDIA11 Protein
TMX Protein
TXNDC Protein
Txndc1 Protein

Bezeichner auf Proteinebene für TMX1

protein disulfide isomerase family A, member 11 , thioredoxin domain containing 1 , thioredoxin domain-containing protein 1 , transmembrane Trx-related protein , Trx-like protein

GENE ID	SPEZIES
81542	Homo sapiens
72736	Mus musculus
362751	Rattus norvegicus
509037	Bos taurus

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