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ALOXE3 Antigen Profile
Beschreibung des Gens
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names and synonyms associated with ALOXE3
arachidonate lipoxygenase 3 (ALOXE3) ELISA Kit
arachidonate lipoxygenase 3 L homeolog (aloxe3.L) ELISA Kit
arachidonate lipoxygenase 3 (aloxe3) ELISA Kit
arachidonate lipoxygenase 3 (Aloxe3) ELISA Kit
arachidonate 15-lipoxygenase, type B (ALOX15B) ELISA Kit
e-lox ELISA Kit
elox3 ELISA Kit
ARCI3 ELISA Kit
E-LOX ELISA Kit
eLOX3 ELISA Kit
e-LOX-3 ELISA Kit
ALOX15B ELISA Kit
Bezeichner auf Proteinebene für ALOXE3
arachidonate lipoxygenase 3
, epidermal lipoxygenase
, epidermis-type lipoxygenase 3
, arachidonate 15-lipoxygenase, type B