anti-Ratte (Rattus) SATB1 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended SATB1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SATB Homeobox 1 (SATB1) Antikörper
  • SATB1
  • 2610306G12Rik
  • AW413156
  • SATB homeobox 1
  • special AT-rich sequence binding protein 1
  • SATB1
  • satb1
  • Satb1
Epitop
AA 700-750
20
15
15
13
8
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
123
59
35
7
5
3
3
2
2
1
1
Wirt
Kaninchen
73
32
18
Klonalität
Polyklonal
Konjugat
Dieser SATB1 Antikörper ist unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
104
52
41
32
26
15
13
11
7
4
3
2
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN732008
$ 306.90
Zzgl. Versandkosten $45.00

General

Antigen SATB Homeobox 1 (SATB1) Antikörper
Epitop AA 700-750
(20), (15), (15), (13), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(123), (59), (35), (7), (5), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(73), (32), (18)
Klonalität
Polyklonal
Konjugat Dieser SATB1 Antikörper ist unkonjugiert
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(104), (52), (41), (32), (26), (15), (13), (11), (7), (4), (3), (2), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SATB1 Antikörper

Target Details SATB1 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse SATB1
Isotyp IgG
Plasmids, Primers & others

Target Details SATB1

Produktdetails anti-SATB1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Satb1 (SATB1 Antibody Abstract)
Hintergrund

Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis (By similarity). Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma. Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes.

Subcellular location: Nucleus

Synonyms: AW413156, 2610306G12Rik, DNA-binding protein SATB1, Special AT-rich sequence-binding protein 1, Satb1

Gen-ID 20230
UniProt Q60611
Pathways Caspase Kaskade in der Apoptose, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-SATB1 Antikörper Target Details SATB1 Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SATB1 Antikörper Target Details SATB1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-SATB1 Antikörper Target Details SATB1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-SATB Homeobox 1 (SATB1) (AA 700-750) antibody (ABIN732008) Formalin-fixed and paraffin embedded human gastric cancer labeled with Anti-SATB1 Pol...
Immunohistochemistry (IHC) image for anti-SATB Homeobox 1 (SATB1) (AA 700-750) antibody (ABIN732008) Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-SATB1 Polyc...