anti-Human GAS2 Antikörper für Immunofluorescence

Recommended GAS2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Growth Arrest-Specific 2 (GAS2) Antikörper
  • GAS2
  • gas2
  • si:packt119.1
  • GAS-2
  • Gas-2
  • RGD1563167
  • growth arrest specific 2
  • growth arrest-specific 2b
  • growth arrest-specific 2
  • GAS2
  • gas2b
  • Gas2
Epitop
AA 1-111
17
12
6
5
4
4
3
2
1
1
Reaktivität
Human, Maus
77
37
31
Wirt
Maus
71
7
Klonalität
Monoklonal
Konjugat
Dieser GAS2 Antikörper ist unkonjugiert
5
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunofluorescence (IF), Western Blotting (WB)
56
33
23
13
9
4
4
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN393205
$ 461.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.680438 ABIN561000 IF ELISA WB Mouse IgG2a kappa AA 1-110, partial Anmelden zum Anzeigen 4E11 1
11.680438 ABIN1872778 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.680438 ABIN3198081 IC IF IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
11.680438 ABIN5966089 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1827970 IF ELISA WB Mouse IgG2a, kappa AA 1-110 Anmelden zum Anzeigen 4E11 0
1 ABIN2888143 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2696733 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2277609 IF ELISA WB Mouse IgG2a kappa AA 1-110 Anmelden zum Anzeigen 4E11 0
1 ABIN5507074 IF IF/ICC Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Growth Arrest-Specific 2 (GAS2) Antikörper
Epitop AA 1-111
(17), (12), (6), (5), (4), (4), (3), (2), (1), (1)
Reaktivität Human, Maus
(77), (37), (31)
Wirt Maus
(71), (7)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser GAS2 Antikörper ist unkonjugiert
(5), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Immunofluorescence (IF), Western Blotting (WB)
(56), (33), (23), (13), (9), (4), (4), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
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Produktdetails anti-GAS2 Antikörper

Target Details GAS2 Anwendungsinformationen Handhabung Referenzen für anti-GAS2 Antikörper (ABIN393205) Bilder
Spezifität GAS2 (NP_005247, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Kreuzreaktivität (Details) Human: ~~ Positive
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen

Antigen Type: Recombinant Protein

Target/Specificity: GAS2 (NP_005247, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon 4E11
Isotyp IgG2a kappa
Plasmids, Primers & others

Target Details GAS2

Produktdetails anti-GAS2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-GAS2 Antikörper (ABIN393205) Bilder zurück nach oben
Antigen
Andere Bezeichnung GAS2 (GAS2 Antibody Abstract)
Hintergrund

Other Names: Growth arrest-specific protein 2, GAS-2, GAS2

Gene Description: growth arrest-specific 2

Gene Summary: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Molekulargewicht 34945 DA
Gen-ID 2620
NCBI Accession NP_005247, NP_001137302, NP_808221
UniProt O43903
Pathways Caspase Kaskade in der Apoptose

Anwendungsinformationen

Produktdetails anti-GAS2 Antikörper Target Details GAS2 Handhabung Referenzen für anti-GAS2 Antikörper (ABIN393205) Bilder zurück nach oben
Applikations-hinweise Western blot = 1:500-1000
Kommentare

Background: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GAS2 Antikörper Target Details GAS2 Anwendungsinformationen Referenzen für anti-GAS2 Antikörper (ABIN393205) Bilder zurück nach oben
Buffer Clear, colorless solution in phosphate buffered saline,  pH 7.2 .
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months

Referenzen für anti-GAS2 Antikörper (ABIN393205)

Produktdetails anti-GAS2 Antikörper Target Details GAS2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006

Benetti, Copetti, DellOrso, Melloni, Brancolini, Monte, Schneider: "The calpain system is involved in the constitutive regulation of beta-catenin signaling functions." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22070-80, 2005

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004

Tsutsumi, Kamata, Vokes, Maruoka, Nakakuki, Enomoto, Omura, Amagasa, Nagayama, Saito-Ohara, Inazawa, Moritani, Yamaoka, Inoue, Itakura: "The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD)." in: American journal of human genetics, Vol. 74, Issue 6, pp. 1255-61, 2004

Bilder

Produktdetails anti-GAS2 Antikörper Target Details GAS2 Anwendungsinformationen Handhabung Referenzen für anti-GAS2 Antikörper (ABIN393205) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) Immunofluorescence of monoclonal antibody to GAS2 on NIH/3T3 cell (antibody concentra...
Immunohistochemistry (IHC) image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (Image 2)
Western Blotting (WB) image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
Western Blotting (WB) image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) Western Blot analysis of GAS2 expression in transfected 293T cell line by GAS2 monocl...
Immunofluorescence (IF) image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) Immunofluorescence of monoclonal antibody to GAS2 on NIH/3T3 cell. [antibody concentr...
ELISA image for anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (ABIN393205) Detection limit for recombinant GST tagged GAS2 is approximately 0.03ng/ml as a captu...