anti-Human F2RL3 Antikörper für ELISA

Recommended F2RL3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) Antikörper
  • F2RL3
  • PAR4
  • F2R like thrombin or trypsin receptor 3
  • F2R like thrombin/trypsin receptor 3
  • coagulation factor II (thrombin) receptor-like 3
  • F2RL3
  • F2rl3
Epitop
AA 18-83
16
15
11
9
6
5
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human
123
61
59
3
2
2
1
1
1
1
1
1
Wirt
Maus
111
14
1
Klonalität
Monoklonal
Konjugat
Dieser F2RL3 Antikörper ist unkonjugiert
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
ELISA, Western Blotting (WB)
70
41
33
27
26
9
7
6
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN396605
$ 461.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.164179 ABIN563904 ELISA WB Mouse IgG1 kappa AA 18-82, partial Anmelden zum Anzeigen 5F4 1
1 ABIN1724706 IHC ELISA WB Mouse IgG1 AA 1-330 Anmelden zum Anzeigen 3G9H7 4
1 ABIN2869311 ELISA IHC WB Mouse IgG1 AA 1-330 Anmelden zum Anzeigen 3G9H7-4H12E9 4
1 ABIN1536156 ELISA WB Rabbit IgG AA 29-78, Cleaved-Gly48 Anmelden zum Anzeigen Polyclonal 1
1 ABIN1536071 IF ELISA WB Rabbit IgG AA 29-78 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3186327 ELISA IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN3186328 ELISA IF WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN1844791 IHC ELISA WB Mouse IgG1 AA 1-330 Anmelden zum Anzeigen 0
1 ABIN3181824 ELISA WB Rabbit IgG Gly48, cleaved Anmelden zum Anzeigen Polyclonal 0
1 ABIN2891216 ELISA WB Rabbit IgG AA 29-78, Cleaved-Gly48 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2891147 IF ELISA WB Rabbit IgG AA 29-78 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4902091 ELISA IHC (p) WB Mouse IgG1 AA 1-330 Anmelden zum Anzeigen 3G9H7-4H12E9 0
1 ABIN6288687 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1456758 ELISA WB Rabbit IgG AA 19-68 Anmelden zum Anzeigen Polyclonal 0
1 ABIN6268176 ELISA WB Rabbit IgG pThr163 Anmelden zum Anzeigen Polyclonal 0
1 ABIN6259627 ELISA ICC IF WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5962728 ELISA IF WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN619480 FACS ELISA Chicken IgY Anmelden zum Anzeigen Polyclonal 1
1 ABIN2470871 IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 3G9H7-4H12E9 0
1 ABIN6268592 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) Antikörper
Epitop AA 18-83
(16), (15), (11), (9), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(123), (61), (59), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Maus
(111), (14), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser F2RL3 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation ELISA, Western Blotting (WB)
(70), (41), (33), (27), (26), (9), (7), (6), (3), (2), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-F2RL3 Antikörper

Target Details F2RL3 Anwendungsinformationen Handhabung Referenzen für anti-F2RL3 Antikörper (ABIN396605) Bilder
Spezifität F2RL3 (NP_003941, 18 a.a. ~ 83 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Kreuzreaktivität (Details) Human: ~~ Positive
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen

Antigen Type: Recombinant Protein

Target/Specificity: F2RL3 (NP_003941, 18 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon 5F4
Isotyp IgG1 kappa
Plasmids, Primers & others

Target Details F2RL3

Produktdetails anti-F2RL3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-F2RL3 Antikörper (ABIN396605) Bilder zurück nach oben
Antigen
Andere Bezeichnung F2RL3 (F2RL3 Antibody Abstract)
Hintergrund

Other Names: Proteinase-activated receptor 4, PAR-4, Coagulation factor II receptor-like 3, Thrombin receptor-like 3, F2RL3, PAR4

Gene Description: coagulation factor II (thrombin) receptor-like 3

Gene Summary: Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq

Molekulargewicht 41133 DA
Gen-ID 9002
NCBI Accession NP_003941
UniProt Q96RI0
Pathways Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process

Anwendungsinformationen

Produktdetails anti-F2RL3 Antikörper Target Details F2RL3 Handhabung Referenzen für anti-F2RL3 Antikörper (ABIN396605) Bilder zurück nach oben
Applikations-hinweise ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Kommentare

Background: Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-F2RL3 Antikörper Target Details F2RL3 Anwendungsinformationen Referenzen für anti-F2RL3 Antikörper (ABIN396605) Bilder zurück nach oben
Buffer Clear, colorless solution in phosphate buffered saline,  pH 7.2 .
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months

Referenzen für anti-F2RL3 Antikörper (ABIN396605)

Produktdetails anti-F2RL3 Antikörper Target Details F2RL3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Ramstrom, ONeill, Dunne, Kenny: "Annexin V binding to platelets is agonist, time and temperature dependent." in: Platelets, Vol. 21, Issue 4, pp. 289-96, 2010

Chen, Tsou, Tsai, Kuo, Chiang, Chang, Fong, Tang: "Thrombin enhanced migration and MMPs expression of human chondrosarcoma cells involves PAR receptor signaling pathway." in: Journal of cellular physiology, Vol. 223, Issue 3, pp. 737-45, 2010

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Megyeri, Makó, Beinrohr, Doleschall, Prohászka, Cervenak, Závodszky, Gál: "Complement protease MASP-1 activates human endothelial cells: PAR4 activation is a link between complement and endothelial function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 5, pp. 3409-16, 2009

Bilder

Produktdetails anti-F2RL3 Antikörper Target Details F2RL3 Anwendungsinformationen Handhabung Referenzen für anti-F2RL3 Antikörper (ABIN396605) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 18-83) antibody (ABIN396605) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
ELISA image for anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 18-83) antibody (ABIN396605) Detection limit for recombinant GST tagged F2RL3 is approximately 0.03ng/ml as a capt...