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Human Monoclonal CXCR1 Primary Antibody für CyTOF, FACS - ABIN4899069
Kline, Donovan, Wellik, Lust, Jin, Moon-Tasson, Xiong, Witzig, Kumar, Rajkumar, Lust: Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. in Leukemia research 2007
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Human Monoclonal CXCR1 Primary Antibody für FACS - ABIN4895414
Maru, Holloway, Flynn, Lancashire, Loughlin, Male, Romero: Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. in Journal of neuroimmunology 2008
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Human Polyclonal CXCR1 Primary Antibody für IF (p), IHC (p) - ABIN730873
Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats. in International journal of clinical and experimental pathology 2014
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Human Monoclonal CXCR1 Primary Antibody für FACS - ABIN4895410
Maxwell, Gallagher, Seaton, Wilson, Scullin, Pettigrew, Stratford, Williams, Johnston, Waugh: HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. in Oncogene 2007
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Human Monoclonal CXCR1 Primary Antibody für FACS, IF - ABIN2689039
Qin, LaRosa, Campbell, Smith-Heath, Kassam, Shi, Zeng, Buthcher, Mackay: Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential. in European journal of immunology 1996
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Human Polyclonal CXCR1 Primary Antibody für IHC (fro), IHC (p) - ABIN152848
Krohn, Kapoor, Enami, Follenzi, Bandi, Joseph, Gupta: Hepatocyte transplantation-induced liver inflammation is driven by cytokines-chemokines associated with neutrophils and Kupffer cells. in Gastroenterology 2009
Human Polyclonal CXCR1 Primary Antibody für ELISA - ABIN4265440
Singh, Nannuru, Sadanandam, Varney, Singh: CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion. in British journal of cancer 2009
Human Polyclonal CXCR1 Primary Antibody für ICC, IHC (p) - ABIN4301121
Ali, Rautemaa, Hietanen, Järvensivu, Richardson, Konttinen: Expression of interleukin-8 and its receptor IL-8RA in chronic hyperplastic candidosis. in Oral microbiology and immunology 2006
Human Monoclonal CXCR1 Primary Antibody für FACS - ABIN4895406
Ghirelli, Zollinger, Soumelis: Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. in Blood 2010
Depletion of receptor accessory proteins REEP5 (zeige REEP5 Antikörper) and REEP6 (zeige REEP6 Antikörper) causes a decrease in CXC Chemokine Receptor 1 (CXCR1) signaling.
increased production of IL-8 (zeige IL8 Antikörper) associated with neutrophils infiltration into the liver and decreased CXCR1/2 expression on peripheral neutrophils. CXCR1 and CXCR2 (zeige CXCR2 Antikörper) expression levels could be served as early markers to predict the severity of acute-on-chronic liver failure.
Chemokine receptor CXCR1 (zeige CX3CR1 Antikörper) could be used as an indicator to predict benign or malignant breast disease, and it can even predict the malignancy degree of breast cancer, as well as its invasive ability and prognosis.
In this review, we summarize the biological functions and clinical significance of the CXCL8 (zeige IL8 Antikörper)-CXCR1/2 signaling pathway in cancer. Targeting CXCL8 (zeige IL8 Antikörper) or CXCR1/2 may be an attractive therapeutic strategy for tumors.
Interaction of Monomeric Interleukin-8 (zeige IL8 Antikörper) with CXCR1
first study to investigate the concentrations of CXCR-1 and CXCR-2 (zeige CXCR2 Antikörper) with the levels of IL-8 (zeige IL8 Antikörper) in colostrum and mature human milk of term and preterm newborns
High expression of CXCR1 identified a subgroup of gastric cancer patients who appeared to benefit from 5-FU based adjuvant chemotherapy .
CXCR1-NFkappaB pathway role in human hepatocyte proliferation
The analysis of IL-8 (interleukin-8 (zeige IL8 Antikörper)), CXCR1 (IL-8RA - IL-8 receptor alpha) and CXCR2 (IL-8RB (zeige CXCR2 Antikörper) - IL-8 receptor beta) expression showed that these molecules are present not only in many different types of inflammatory and endothelial cells, but also in several tumor basaloid, transitional and even few ghost cells.
Study shows that CXCR1 promoted gastric cancer cell proliferation, migration and invasion.
these studies define CXCR1 as a novel, noncanonical chemokine receptor that regulates pulmonary anti-Pseudomonas host defense with broad implications for cystic fibrosis (zeige S100A8 Antikörper), chronic obstructive pulmonary disease and other infectious lung diseases
CXCR1 and CXCR2 (zeige CXCR2 Antikörper) regulate hepatocyte exosome release. The mechanism utilized by CXCR1 remains elusive, but CXCR2 (zeige CXCR2 Antikörper) appears to modulate Nsm activity and resultant production of ceramide to control exosome release. CXCR1 is required for packaging of enzymes into exosomes that mediate their hepatocyte proliferative effect.
These data demonstrate a biological function for mouse Cxcr1 in vivo and indicate that CXCR1-dependent neutrophil effector function is a critical innate protective mechanism of fungal clearance and host survival in systemic candidiasis.
in view of recently-published experimental data obtained in NOD mice, we argue for possible Cxcr1 involvement in type 1 diabetes pathogenesi
CXCR1 expression is induced in staphylococcus aureus-infected macrophages but not in control macrophages.
Pharmacologic blockade of CXCR1/2 as well as genetic deletion of NAP-2 (zeige PPBP Antikörper) markedly reduced leukocyte shape change and intrathrombus migration.
Blockade of the CXCL1 (zeige CXCL1 Antikörper)-CXCR1/2 axis in mice improved intrahepatic islet engraftment. The CXCR1/2-mediated pathway is a regulator of islet damage.
Upon activation by CXCL8 (zeige IL8 Antikörper), CXCR1 predominantly couples to G protein-coupled receptor (zeige GPR34 Antikörper) kinase (GRK)2 (zeige ADRBK1 Antikörper) to modulate leukocyte functions.
Xiaotan Sanjie Decoction XTSJD can decrease the protein expressions of IL-8 (zeige IL8 Antikörper) and its receptors CXCR1/CXCR2 (zeige CXCR2 Antikörper) in tumor xenografts and gastric tissue adjacent to the tumor.
data suggest that CXCR1 does not mediate the proliferative effects of ELR+ CXC chemokines during liver regeneration after partial hepatectomy
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
C-X-C chemokine receptor type 1
, IL-8 receptor type 1
, IL-8R A
, high affinity interleukin-8 receptor A
, interleukin 8 receptor, alpha
, interleukin-8 receptor type 1
, interleukin-8 receptor type A
, CXC chemokine receptor 1
, chemokine (C-X-C motif) receptor 2
, interleukin 8 receptor, beta
, interleukin 8 receptor alpha
, IL-8 receptor
, C-X-C motif chemokine receptor 1 S homeolog
, CXCR2 like protein
, chemokine (C-X-C motif) receptor 1 S homeolog