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anti-Human CCR2 Antikörper:
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Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895496
Tsujioka, Imanishi, Ikejima, Kuroi, Takarada, Tanimoto, Kitabata, Okochi, Arita, Ishibashi, Komukai, Kataiwa, Nakamura, Hirata, Tanaka, Akasaka: Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. in Journal of the American College of Cardiology 2009
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Human Monoclonal CCR2 Primary Antibody für CyTOF, FACS - ABIN4899089
Manley, Caso, Works, Cutler, Zemlyak, Sun, Munhoz, Chang, Sorrells, Ermini, Decker, Bertrand, Dinkel, Steinberg, Sapolsky: Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. in PLoS ONE 2013
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Mouse (Murine) Monoclonal CCR2 Primary Antibody für FACS - ABIN4898202
Benencia, Harshman, Duran-Ortiz, Lubbers, List, Householder, Al-Naeeli, Liang, Welch, Kopchick, Berryman: Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations. in Endocrinology 2015
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Mouse (Murine) Monoclonal CCR2 Primary Antibody für FACS - ABIN4898196
Mikami, Sueda, Ogitani, Otani, Takatsuji, Wada, Watanabe, Yoshikawa, Nishioka, Hashimoto, Miyagi, Fukada, Yamamoto, Tsujikawa: Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions. in PLoS ONE 2014
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Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895487
Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011
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Mouse (Murine) Monoclonal CCR2 Primary Antibody für FACS - ABIN4898198
Levy, Milikovsky, Baranauskas, Vinogradov, David, Ketzef, Abutbul, Weissberg, Kamintsky, Fleidervish, Friedman, Monsonego: Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895488
Dagouassat, Suffee, Hlawaty, Haddad, Charni, Laguillier, Vassy, Martin, Schischmanoff, Gattegno, Oudar, Sutton, Charnaux: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. in International journal of cancer 2010
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Human Polyclonal CCR2 Primary Antibody für FACS, ICC - ABIN4288963
Carlson, Helterline, Asbe, Dupras, Minami, Farris, Stempien-Otero: Cardiac macrophages adopt profibrotic/M2 phenotype in infarcted hearts: Role of urokinase plasminogen activator. in Journal of molecular and cellular cardiology 2016
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Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895492
Kanabar, Tedaldi, Jiang, Nie, Panina, Descroix, Man, Pitchford, Page, Wagner: Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes. in Glycobiology 2016
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Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895490
Campanelli, Fois, Catarsi, Poletto, Villani, Erba, Maddaluno, Jemos, Salmoiraghi, Guglielmelli, Abbonante, Di Buduo, Balduini, Iurlo, Barosi, Rosti, Massa: Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis. in PLoS ONE 2016
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T cell-stimulated CLL cells actively recruited monocytes; recruitment critically depended on the C-C-motif-chemokine-receptor-2 axis.
Study found that the activation of CCR2 by its ligand CCL2 (zeige CCL2 Antikörper) increased the expression of SMO and Gli-1 (zeige GLI1 Antikörper), resulting in Hh pathway activation, epithelial-mesenchymal transition and hepatocellular carcinoma cell invasion.
results confirmed that the CCR2 3'UTR acts as a metastasis suppressor by acting as a ceRNA for STARD13 and thus inhibiting RhoA-ROCK1-MLC-F-actin pathway in breast cancer cells.
It can be concluded that MCP-1 and CCR2 polymorphisms are not associated with AgP in Turkish population.
beta-arrestin2/AP-1-dependent beta2AR signaling has a critical role in the regulation of CCR2 expression and recruitment of leukocytes to the heart following injury
Results indicated that MCP-1 and CCR2 polymorphisms may influence the progression of IgAN, but not increase/decrease its susceptibility
High CCR2 expression is associated gastric cancer.
Our data strongly support the use of CCR2 and CD180 (zeige CD180 Antikörper) mRNAs as whole blood pharmacodynamic (PD)biomarkers for BRD4 (zeige BRD4 Antikörper) inhibitors, especially in situations where paired tumor biopsies are unavailable. In addition, they can be used as tumor-based PD biomarkers for hematologic tumors.
Through experiments with chimeras of MCP-1 and MCP-3, we identified the chemokine amino-terminal region as being the primary determinant of both the binding and signaling selectivity of these two chemokines at CCR2.
Comprehensive Computational Analysis of GWAS Loci Identifies CCR2 as a Candidate Gene for Celiac Disease Pathogenesis
Enhanced bacterial clearance in CCR2(-/-) mice correlated with reduced numbers of IMs in spleens and increased numbers of neutrophils in livers.
Inflammatory CCR2(+) cells that reach the injured kidney at initial stages.
ANG II is up-regulated in serum and heart tissues of mice with EAM and that ANG II significantly drives monocyte/macrophage infiltration through the C-C chemokine receptor 2/5 (CCR2/5) axis.
this study shows that CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1 (zeige TNFRSF1A Antikörper)
this paper shows CCR2(-) and CCR2(+) corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion
this study shows that the chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis
Although CCR2 and CX3CR1 (zeige CX3CR1 Antikörper) may synergistically impact inflammatory phenotypes, their joint deficiency did not influence the metabolic effects of a 45% high-fat diet-induced obesity in these model conditions.
Chemokine receptor 2 (CCR2(+)) monocytes invade the hippocampus between 1 and 3 d after SE. In contrast, only an occasional CD3 (zeige CD3E Antikörper)(+) T lymphocyte was encountered 3 d after SE. The initial cellular sources of the chemokine (zeige CCL1 Antikörper) CCL2 (zeige CCL2 Antikörper), a ligand for CCR2, included perivascular macrophages and microglia. The induction of the proinflammatory cytokine IL-1beta (zeige IL1B Antikörper) was greater in FACS-isolated microglia than in brain-invading monocytes
TLR9-driven inflammation induced a Ccr2-independent expansion of functionally enhanced extramedullary myeloid progenitors that correlated with the peripheral accumulation of monocytes in both wild-type and Ccr2(-/-) mice.
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
C-C chemokine receptor type 2
, MCP-1 receptor
, monocyte chemoattractant protein 1 receptor
, monocyte chemotactic protein 1 receptor
, C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)
, C-C CKR-2
, JE/FIC receptor
, MIP-1 alphaR
, chemoattractant protein-1 receptor
, chemokine (C-C) receptor 2
, chemokine receptor CCR2
, chemokine receptor