anti-Human CEBPA Antikörper für Immunofluorescence

Recommended CEBPA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Antikörper
  • C/EBP-alpha
  • CEBP
  • C/ebpalpha
  • CBF-A
  • Cebp
  • DBPCEP
  • c/ebpa
  • cb1062
  • wu:fj20f03
  • C/EBP
  • C/EBPalpha
  • xC/EBP
  • cC/EBP
  • C/EBP alpha
  • CCAAT/enhancer binding protein alpha
  • CCAAT/enhancer binding protein (C/EBP), alpha
  • CCAAT/enhancer binding protein alpha L homeolog
  • CEBPA
  • Cebpa
  • cebpa
  • cebpa.L
Reaktivität
Human
165
100
86
10
7
5
5
5
4
4
3
2
1
1
1
Wirt
Maus
129
39
3
2
Klonalität
Monoklonal
Konjugat
Dieser CEBPA Antikörper ist unkonjugiert
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF)
142
72
48
28
26
15
12
8
4
3
3
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2664083
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.948685 ABIN1106663 EIA FACS IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 5B7 1
11.948685 ABIN4297605 ELISA FACS ICC IF IHC WB Mouse IgG1 Anmelden zum Anzeigen 5B7
11.948685 ABIN5075854 ICC IF Rabbit IgG Anmelden zum Anzeigen Polyclonal
11.948685 ABIN5075855 ICC IF Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN269606 FACS ICC IF IP WB Mouse IgG Anmelden zum Anzeigen 15C8 4
1 ABIN1497467 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 5B7
1 ABIN4297609 IF WB Chicken IgY N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2443970 IF WB Chicken N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Antikörper
Reaktivität Human
(165), (100), (86), (10), (7), (5), (5), (5), (4), (4), (3), (2), (1), (1), (1)
Wirt Maus
(129), (39), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CEBPA Antikörper ist unkonjugiert
(4), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF)
(142), (72), (48), (28), (26), (15), (12), (8), (4), (3), (3), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CEBPA Antikörper

Target Details CEBPA Anwendungsinformationen Handhabung Referenzen für anti-CEBPA Antikörper (ABIN2664083) Bilder
Kreuzreaktivität Maus
Kreuzreaktivität (Details) weakly cross-reacts with mouse
Reinigung The antibody was purified by affinity chromatography.
Klon 16C12B70
Isotyp IgG2a kappa

Target Details CEBPA

Produktdetails anti-CEBPA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CEBPA Antikörper (ABIN2664083) Bilder zurück nach oben
Antigen
Andere Bezeichnung C/EBPalpha (CEBPA Antibody Abstract)
Hintergrund The CCAAT-enhancer binding proteins (C/EBP) are members of the basic region/leucine zipper (bZIP) transcription factors, that bind to the consensus CCAAT sequence in DNA. C/EBPα is expressed in two isoforms: p42 and p30 by ultilizing different translational start codons. The C/EBPα p30 isoform has little to no transactivating activity and acts as an inhibitor. C/EBPα regulates expression of various myeloid-specific genes and is required for myeloid differentiation. C/EBPα has been found to play a key role in adipogenesis, since inhibition of C/EBPα blocks adipocyte differentiation. C/EBPα also regulates cell cycle progression through interactions with cyclin-dependent kinases (CDK) and by inducing the expression of CDK inhibitor p21. Mutations in the C/EBPα gene are associated with the development of acute myeloid leukemia.
Pathways Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Anwendungsinformationen

Produktdetails anti-CEBPA Antikörper Target Details CEBPA Handhabung Referenzen für anti-CEBPA Antikörper (ABIN2664083) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CEBPA Antikörper Target Details CEBPA Anwendungsinformationen Referenzen für anti-CEBPA Antikörper (ABIN2664083) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CEBPA Antikörper (ABIN2664083)

Produktdetails anti-CEBPA Antikörper Target Details CEBPA Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

De Obaldia, Bell, Wang, Harly, Yashiro-Ohtani, DeLong, Zlotoff, Sultana, Pear, Bhandoola: "T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1." in: Nature immunology, Vol. 14, Issue 12, pp. 1277-84, 2013

Fan, Liu, Johnson, Richards: "CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 2, pp. 253-68, 2011

Di Tullio, Vu Manh, Schubert, Castellano, Månsson, Graf: "CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 41, pp. 17016-21, 2011

Cai, Wang, Keefer, Yeamans, Hensley, Friedman: "C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1." in: Oncogene, Vol. 27, Issue 19, pp. 2772-9, 2008

Khanna-Gupta: "Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBP alpha)." in: Blood cells, molecules & diseases, Vol. 41, Issue 1, pp. 77-81, 2008

Bilder

Produktdetails anti-CEBPA Antikörper Target Details CEBPA Anwendungsinformationen Handhabung Referenzen für anti-CEBPA Antikörper (ABIN2664083) zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody (ABIN2664083) anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
Western Blotting (WB) image for anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody (ABIN2664083) anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody (Image 2)