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anti-Human RAB14 Antikörper:
anti-Mouse (Murine) RAB14 Antikörper:
anti-Rat (Rattus) RAB14 Antikörper:
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Cow (Bovine) Polyclonal RAB14 Primary Antibody für IHC, WB - ABIN2792300
Junutula, De Maziére, Peden, Ervin, Advani, van Dijk, Klumperman, Scheller: Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. in Molecular biology of the cell 2004
Show all 3 Pubmed References
Human Polyclonal RAB14 Primary Antibody für ICC, IF - ABIN4348883
Gundry, Marco, Rainero, Miller, Dornier, Mitchell, Caswell, Campbell, Hogeweg, Sansom, Morton, Norman: Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion. in Nature communications 2017
The results from this analysis indicated that Rab11a (zeige RAB11A Antikörper), Rab11c(Rab25 (zeige RAB25 Antikörper)) and Rab14 were expressed in a wide range of cell lines, including the human placental trophoblastic BeWo cell line.
acst as oncogene (zeige RAB1A Antikörper) and Induces proliferation of gastric cancer cells via AKT (zeige AKT1 Antikörper) signaling pathway
Rab14-specific siRNA-induced downregulation of Rab14 increases the sensitivity to cisplatin, while forced expression of Rab14 lacking 3'-UTR (zeige UTS2R Antikörper) abrogated the pro-apoptotic function of miR (zeige MLXIP Antikörper)-148a in renal cancer cells. miR (zeige MLXIP Antikörper)-148a acts as a tumor suppressor and holds great potential for renal cancer therapy by directly targeting Rab14.
PKCiota binds to Rab14 and that PKCiota requires Rab14 for its correct distribution in cells. As with Rab14, PKCiota protects claudin-2 (zeige CLDN2 Antikörper) from lysosomal degradation and, in consequence, modulates epithelial barrier.
We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes.
RAB14 is a direct target of both MIR144 and MIR451. As MIR144 and MIR451 expression increased during human erythropoiesis, RAB14 protein expression decreased. RAB14 as a novel physiological inhibitor of human erythropoiesis.
the miR (zeige MLXIP Antikörper)-451/RAB14 interaction plays an important role in the enhancement of radiosensitivity in NPC (zeige NPC1 Antikörper) cells.
Data indicate that myosin Va (zeige MYO5A Antikörper) interacted with multiple new Rab (zeige HRB Antikörper) subfamilies including Rab6 (zeige RAB6A Antikörper), Rab14 and Rab39B (zeige RAB39B Antikörper).
Rab5a (zeige RAB5A Antikörper), Rab8a (zeige RAB8A Antikörper) and Rab14 are major regulators of MT1-MMP (zeige MMP14 Antikörper) trafficking and invasive migration of primary human macrophages.
Data indicate taht the parasitophorous vacuole (PV), marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space.
clear effect of subcutaneous zoledronic acid administration in vivo on the prenylation of Rab1A (zeige RAB1A Antikörper), Rab5B (zeige RAB5B Antikörper), Rab7A (zeige RAB7A Antikörper) and Rab14 in mouse peritoneal macrophages, confirming that systemic treatment with bisphosphonate drug can inhibit prenylation in myeloid cells in vivo outside the skeleton.
findings provide compelling evidence that Rab22a plays a central role in the MHC-I endocytic trafficking, which is crucial for efficient cross-presentation by dendritic cells
Rab14 limits the sorting of Glut4 (zeige SLC2A4 Antikörper) from endosomes into insulin (zeige INS Antikörper)-sensitive regulated secretory compartments in adipocytes.(
Rab14 activity promotes phagosome maturation during C. albicans infection but is dysregulated on the phagosome in the presence of the invasive hyphal form, which favors fungal survival and escape.
RAB14 functions upstream of RAB10 (zeige RAB10 Antikörper) in the sorting of GLUT4 (zeige SLC2A4 Antikörper) to the specialized transport vesicles that ferry GLUT4 (zeige SLC2A4 Antikörper) to the plasma membrane.
the primary role of Rab14 in GLUT4 (zeige SLC2A4 Antikörper) trafficking is to control the transit of internalised GLUT4 (zeige SLC2A4 Antikörper) from early endosomes into the Golgi complex, rather than direct GLUT4 (zeige SLC2A4 Antikörper) translocation to the plasma membrane.
Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.
The kinesin-3 motor KIF16B (zeige KIF16B Antikörper)/Rab14 complex acts in biosynthetic Golgi-to-endosome traffic of the fibroblast growth factor receptor (FGFR) during early embryonic development.
Rab14 enables mycobacterial phagosomes to maintain early endosomal characteristics and avoid late endosomal/lysosomal degradative components.
The complete coding sequences of three porcine genes--RAB14, S35A3 and ITM2A (zeige ITM2A Antikörper) were amplified and nucleotide sequence and tissue expression were analysed.
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004
F protein-binding protein 1
, bA165P4.3 (member RAS oncogene family)
, ras-related protein Rab-14
, small GTP binding protein RAB14
, GTPase Rab14
, RAB14, member RAS oncogene family
, rab14, member ras oncogene family
, RAB22, member RAS oncogene family
, ras-related protein Rab-22A