anti-Human TNFRSF12A Antikörper für Blocking Reagent

Recommended TNFRSF12A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antikörper
  • CD266
  • FN14
  • TWEAKR
  • AI255180
  • C87282
  • Fn14
  • HPIP
  • TWEAK-R
  • TweakR
  • TNF receptor superfamily member 12A
  • tumor necrosis factor receptor superfamily, member 12a
  • TNFRSF12A
  • Tnfrsf12a
Reaktivität
Human
91
60
30
3
3
2
2
2
2
1
1
1
Wirt
Maus
48
42
9
1
Klonalität
Monoklonal
Konjugat
Dieser TNFRSF12A Antikörper ist unkonjugiert
11
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Blocking Reagent (BR), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
57
46
26
14
13
12
11
10
3
3
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2666428
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General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antikörper
Reaktivität Human
(91), (60), (30), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Maus
(48), (42), (9), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TNFRSF12A Antikörper ist unkonjugiert
(11), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Blocking Reagent (BR), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
(57), (46), (26), (14), (13), (12), (11), (10), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TNFRSF12A Antikörper

Target Details TNFRSF12A Anwendungsinformationen Handhabung Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428) Bilder
Marke LEAF™
Reinigung The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterilität 0.2 μm filtered
Endotoxin-Niveau

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Klon ITEM-1
Isotyp IgG1 kappa
Plasmids, Primers & others

Target Details TNFRSF12A

Produktdetails anti-TNFRSF12A Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD266 (TNFRSF12A Antibody Abstract)
Hintergrund TWEAK receptor is also known as fibroblast growth factor inducible 14 kD protein (Fn14) or CD266. It is a 14 kD transmembrane protein that is expressed on a variety of tissue types. This receptor binds TWEAK and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The TWEAK receptor is rapidly induced during liver regeneration and m play a role in hepatocyte growth. TWEAK receptor engagement can induce cell death and may play a role in inflammation. The ITEM-1 antibody is useful for flow cytometric analysis, induction of tumor cells apoptosis or necrotic cell death, enhancing endothelial cell proliferation, and immunohistochemistry on frozen tissues.
Pathways Apoptose, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-TNFRSF12A Antikörper Target Details TNFRSF12A Handhabung Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TNFRSF12A Antikörper Target Details TNFRSF12A Anwendungsinformationen Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Konservierungs-mittel Azide free
Lagerung 4 °C

Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428)

Produktdetails anti-TNFRSF12A Antikörper Target Details TNFRSF12A Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Muñoz-García, Martín-Ventura, Martínez, Sánchez, Hernández, Ortega, Ortiz, Egido, Blanco-Colio: "Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin." in: Stroke; a journal of cerebral circulation, Vol. 37, Issue 8, pp. 2044-53, 2006

Felli, Pedini, Zeuner, Petrucci, Testa, Conticello, Biffoni, Di Cataldo, Winkles, Peschle, De Maria: "Multiple members of the TNF superfamily contribute to IFN-gamma-mediated inhibition of erythropoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 3, pp. 1464-72, 2005

Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: "Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 341-8, 2002

Feng, Guo, Factor, Thorgeirsson, Bell, Testa, Peifley, Winkles: "The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas." in: The American journal of pathology, Vol. 156, Issue 4, pp. 1253-61, 2000

Meighan-Mantha, Hsu, Guo, Brown, Feng, Peifley, Alberts, Copeland, Gilbert, Jenkins, Richards, Winkles: "The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration." in: The Journal of biological chemistry, Vol. 274, Issue 46, pp. 33166-76, 2000

Lynch, Wang, Lund, Chen, Leal, Wiley: "TWEAK induces angiogenesis and proliferation of endothelial cells." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8455-9, 1999

Bilder

Produktdetails anti-TNFRSF12A Antikörper Target Details TNFRSF12A Anwendungsinformationen Handhabung Referenzen für anti-TNFRSF12A Antikörper (ABIN2666428) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibody (ABIN2666428) anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibody