anti-Hund Lamin A/C Antikörper für Immunohistochemistry

Recommended Lamin A/C Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Lamin A/C (LMNA) Antikörper
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Reaktivität
Human, Ratte (Rattus), Maus, Rind (Kuh), Hund
449
272
235
98
52
49
25
22
17
10
10
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Wirt
Maus
240
217
5
3
Klonalität
Monoklonal
Konjugat
Dieser Lamin A/C Antikörper ist unkonjugiert
13
12
10
7
7
6
6
6
6
6
6
6
5
5
5
5
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC), Western Blotting (WB)
415
205
198
154
121
112
76
71
54
17
15
11
2
2
1
1
1
1
Optionen
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Produktnummer ABIN335389
$ 383.89
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
22.634544 ABIN335390 ICC FACS IHC (fro) IHC WB Mouse IgG1 Anmelden zum Anzeigen 131C3 3
9.997215 ABIN218314 IHC IHC (p) WB Rabbit IgG AA 249-266 Anmelden zum Anzeigen Polyclonal 0
1 ABIN201197 FACS ICC IHC IHC (fro) WB Mouse IgG3, kappa AA 598-611 Anmelden zum Anzeigen 0
1 ABIN201198 ICC IHC IHC (fro) WB Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 0
1 ABIN2469601 IHC WB Rabbit IgG AA 249-266 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1910113 IF IHC IHC (p) IP WB Rabbit IgG AA 550-600 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1910109 IF IHC IHC (p) IP WB Rabbit IgG AA 1-50 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1910112 IF IHC IHC (p) WB Rabbit IgG AA 400-450 Anmelden zum Anzeigen Polyclonal 0
-3.8422852 ABIN4329985 CyTOF FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-6.842285 ABIN4330009 CyTOF FACS ICC IF IHC IHC (fro) WB Mouse IgG1 AA 319-566 Anmelden zum Anzeigen 131C3 0
-12.842285 ABIN4329990 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 488 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329994 ICC IF IHC IHC (fro) WB Biotin Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4330000 FACS ICC IF IHC IHC (fro) WB DyLight 755 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4330004 FACS ICC IF IHC IHC (fro) WB DyLight 350 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4330005 FACS ICC IF IHC IHC (fro) WB DyLight 405 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329991 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 647 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329992 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 700 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329997 FACS ICC IF IHC IHC (fro) WB DyLight 680 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329998 FACS ICC IF IHC IHC (fro) WB DyLight 488 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0
-12.842285 ABIN4329989 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 405 Mouse IgG3 AA 598-611 Anmelden zum Anzeigen 133A2 0

General

Antigen Lamin A/C (LMNA) Antikörper
Reaktivität Human, Ratte (Rattus), Maus, Rind (Kuh), Hund
(449), (272), (235), (98), (52), (49), (25), (22), (17), (10), (10), (9), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Maus
(240), (217), (5), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Lamin A/C Antikörper ist unkonjugiert
(13), (12), (10), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC), Western Blotting (WB)
(415), (205), (198), (154), (121), (112), (76), (71), (54), (17), (15), (11), (2), (2), (1), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Lamin A/C Antikörper

Target Details Lamin A/C Anwendungsinformationen Handhabung Referenzen für anti-Lamin A/C Antikörper (ABIN335389) Bilder
Spezifität Human, rat, mouse, bovine, dog.
Reinigung Purified
Immunogen 133A2 is a mouse monoclonal IgG3/kappa antibody obtained from fusion of P3/X63.Ag8.653 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with partially purified recombinant human lamin A.
Klon 133A2
Isotyp IgG3
Plasmids, Primers & others

Target Details Lamin A/C

Produktdetails anti-Lamin A/C Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Lamin A/C Antikörper (ABIN335389) Bilder zurück nach oben
Antigen
Andere Bezeichnung Lamin A (LMNA Antibody Abstract)
Hintergrund Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.
Pathways Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Lamin A/C Antikörper Target Details Lamin A/C Handhabung Referenzen für anti-Lamin A/C Antikörper (ABIN335389) Bilder zurück nach oben
Applikations-hinweise 133A2 recognizes an epitope located between residues 598-611 of lamin A and therefore 133A2 reacts exclusively with lamin A. 133A2 is suitable for immunocytochemistry, immunohistochemistry on frozen sections, immunoblotting and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Lamin A/C Antikörper Target Details Lamin A/C Anwendungsinformationen Referenzen für anti-Lamin A/C Antikörper (ABIN335389) Bilder zurück nach oben
Lagerung 4 °C

Referenzen für anti-Lamin A/C Antikörper (ABIN335389)

Produktdetails anti-Lamin A/C Antikörper Target Details Lamin A/C Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Broers, Bronnenberg, Kuijpers, Schutte, Hutchison, Ramaekers: "Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis." in: European journal of cell biology, Vol. 81, Issue 12, pp. 677-91, 2003

Broers, Machiels, van Eys, Kuijpers, Manders, van Driel, Ramaekers: "Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins." in: Journal of cell science, Vol. 112 ( Pt 20), pp. 3463-75, 2000

Neri, Raymond, Giordano, Borgatti, Marchisio, Capitani, Martelli: "Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions." in: Journal of cellular biochemistry, Vol. 75, Issue 1, pp. 36-45, 1999

Neri, Raymond, Giordano, Capitani, Martelli: "Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells." in: Journal of cellular physiology, Vol. 178, Issue 3, pp. 284-95, 1999

Pugh, Coates, Lane, Raymond, Quinlan: "Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells." in: Journal of cell science, Vol. 110 ( Pt 19), pp. 2483-93, 1997

Broers, Machiels, Kuijpers, Smedts, van den Kieboom, Raymond, Ramaekers: "A- and B-type lamins are differentially expressed in normal human tissues." in: Histochemistry and cell biology, Vol. 107, Issue 6, pp. 505-17, 1997

Jansen, Machiels, Hopman, Broers, Bot, Arends, Ramaekers, Schouten: "Comparison of A and B-type lamin expression in reactive lymph nodes and nodular sclerosing Hodgkin's disease." in: Histopathology, Vol. 31, Issue 4, pp. 304-12, 1997

Machiels, Ramaekers, Kuijpers, Groenewoud, Oosterhuis, Looijenga: "Nuclear lamin expression in normal testis and testicular germ cell tumours of adolescents and adults." in: The Journal of pathology, Vol. 182, Issue 2, pp. 197-204, 1997

Machiels, Broers, Raymond, de Ley, Kuijpers, Caberg, Ramaekers: "Abnormal A-type lamin organization in a human lung carcinoma cell line." in: European journal of cell biology, Vol. 67, Issue 4, pp. 328-35, 1996

Hozák, Sasseville, Raymond, Cook: "Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells." in: Journal of cell science, Vol. 108 ( Pt 2), pp. 635-44, 1995

Bilder

Produktdetails anti-Lamin A/C Antikörper Target Details Lamin A/C Anwendungsinformationen Handhabung Referenzen für anti-Lamin A/C Antikörper (ABIN335389) zurück nach oben
Bilder des Herstellers
 image for anti-Lamin A/C (LMNA) antibody (ABIN335389) anti-Lamin A/C (LMNA) antibody
 image for anti-Lamin A/C (LMNA) antibody (ABIN335389) Immunocytochemical staining of fiboblasts showing nuclear lamina