anti-Maus Caspase 4 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • CASP13
  • CASP1
  • CASP4
  • Caspl
  • ich-3
  • Casp4
  • caspase 4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4
  • CASP4
  • Casp4
  • LOC100731032
Reaktivität
Human, Maus
197
111
51
21
3
1
1
Wirt
Ratte
207
27
21
17
7
Klonalität
Monoklonal
Konjugat
Dieser Caspase 4 Antikörper ist unkonjugiert
19
16
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
256
92
91
57
30
24
18
17
17
13
10
3
2
1
1
Hersteller
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Bilder

Produktnummer ABIN265762
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
10.026257 ABIN498677 IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
10.026257 ABIN872827 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10.026257 ABIN4288127 ELISA ICC IF IHC IHC (p) WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
10.026257 ABIN4288126 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN462473 IHC IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5554659 EIA IF IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2477914 IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 3
1 ABIN121890 IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 4
1 ABIN214595 IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN303366 IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN1732653 IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN609267 IHC IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN609266 IHC IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN4288032 ELISA ICC IF IHC IHC (fro) IHC (p) IP MA WB Rat IgG2a Anmelden zum Anzeigen 17D9 0
1 ABIN2893038 IHC IHC (p) WB Rabbit Glu124 Anmelden zum Anzeigen Polyclonal 0
1 ABIN320487 IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN4288036 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 647 Rat IgG2a Anmelden zum Anzeigen 17D9 0
1 ABIN4288034 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Rat IgG2a Anmelden zum Anzeigen 17D9 0
1 ABIN4288035 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rat IgG2a Anmelden zum Anzeigen 17D9 0
1 ABIN4288037 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 700 Rat IgG2a Anmelden zum Anzeigen 17D9 0

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper
Reaktivität Human, Maus
(197), (111), (51), (21), (3), (1), (1)
Wirt Ratte
(207), (27), (21), (17), (7)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Caspase 4 Antikörper ist unkonjugiert
(19), (16), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
(256), (92), (91), (57), (30), (24), (18), (17), (17), (13), (10), (3), (2), (1), (1)
Pubmed 23 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 4 Antikörper

Target Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder
Reinigung Protein G purified
Immunogen A recombinant p30 subunit of mouse Caspase 11. [UniProt# P70343]
Klon 17D9
Isotyp IgG2a
Plasmids, Primers & others

Target Details Caspase 4

Produktdetails anti-Caspase 4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Antigen
Andere Bezeichnung Caspase-11 (CASP4 Antibody Abstract)
Hintergrund Gene Symbol: CASP11
Molekulargewicht Theoretical MW: 35-43 kDa
Gen-ID 12363
UniProt P70343
Pathways Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Applikations-hinweise Western Blot 5 μg/mL, ELISA, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:100, Immunoprecipitation, Immunohistochemistry-Paraffin 1:100, Immunohistochemistry-Frozen 1:10-1:500, MicroarrayUse in immunprecipitation reported in scientific literature (PMID 10791975) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-Caspase 4 Antikörper (ABIN265762)

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Man, Karki, Briard, Burton, Gingras, Pelletier, Kanneganti: "Differential roles of caspase-1 and caspase-11 in infection and inflammation." in: Scientific reports, Vol. 7, pp. 45126, 2017 (Probematerial (Species): Mouse (Murine)).

Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Cheng, Xiong, Ye, Hong, Di, Tsang, Gao, An, Mittal, Vogel, Miao, Rehman, Malik: "Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury." in: The Journal of clinical investigation, Vol. 127, Issue 11, pp. 4124-4135, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Chung, Vilaysane, Lau, Stahl, Morampudi, Bondzi-Simpson, Platnich, Bracey, French, Beck, Chun, Vallance, Muruve: "NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1331-46, 2016 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kim, Bae, Ryu, Kwon, Oh, Kwon, Moon, Kim, Miyawaki, Lee, Shin, Kim, Kim, Ryter, Choi, Rhee, Ryu, Yoon: "SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages." in: Autophagy, Vol. 12, Issue 8, pp. 1272-91, 2016 Weitere Details: Western Blotting,Immunoprecipitation

Klaska, Muckersie, Martin-Granados, Christofi, Forrester: "Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms." in: Immunology, Vol. 150, Issue 3, pp. 364-377, 2016

Youm, Nguyen, Grant, Goldberg, Bodogai, Kim, DAgostino, Planavsky, Lupfer, Kanneganti, Kang, Horvath, Fahmy, Crawford, Biragyn, Alnemri, Dixit: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." in: Nature medicine, Vol. 21, Issue 3, pp. 263-9, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Aachoui, Kajiwara, Leaf, Mao, Ting, Coers, Aderem, Buxbaum, Miao: "Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium." in: Cell host & microbe, Vol. 18, Issue 3, pp. 320-32, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Shi, Zhao, Wang, Shi, Wang, Huang, Zhuang, Cai, Wang, Shao: "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death." in: Nature, Vol. 526, Issue 7575, pp. 660-5, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kayagaki, Stowe, Lee, ORourke, Anderson, Warming, Cuellar, Haley, Roose-Girma, Phung, Liu, Lill, Li, Wu, Kummerfeld, Zhang, Lee, Snipas, Salvesen, Morris, Fitzgerald, Zhang, Bertram, Goodnow, Dixit: "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling." in: Nature, Vol. 526, Issue 7575, pp. 666-71, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Diabate, Munro, Garcia, Jacquel, Michel, Obba, Goncalves, Luci, Marchetti, Demon, Degos, Bechah, Mege, Lamkanfi, Auberger, Gorvel, Stuart, Landraud, Lemichez, Boyer: "Escherichia coli ?-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004732, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: ELISA

Bonora, Wieckowsk, Chinopoulos, Kepp, Kroemer, Galluzzi, Pinton: "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition." in: Oncogene, Vol. 34, Issue 12, pp. 1608, 2015

Yuan, Syed, Panchal, Joo, Colonna, Brantly, Sadikot: "Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 15118-29, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Gurung, Anand, Malireddi, Vande Walle, Van Opdenbosch, Dillon, Weinlich, Green, Lamkanfi, Kanneganti: "FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1835-46, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Van Opdenbosch, Gurung, Vande Walle, Fossoul, Kanneganti, Lamkanfi: "Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation." in: Nature communications, Vol. 5, pp. 3209, 2014 Weitere Details: Western Blotting

Case, Kohler, Lima, Strowig, de Zoete, Flavell, Zamboni, Roy: "Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1851-6, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Jin, Oda, Lai, Skalsky, Bethel, Shepherd, Kang, Liu, Sabouri-Ghomi, Cullen, Rajewsky, Xiao: "MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways." in: The EMBO journal, Vol. 32, Issue 17, pp. 2377-91, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: "An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1." in: The Biochemical journal, Vol. 443, Issue 2, pp. 355-9, 2012 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Sun, Wu, Hayashi, Peters, Tsuda, Inoue, Nakanishi: "Microglial cathepsin B contributes to the initiation of peripheral inflammation-induced chronic pain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 33, pp. 11330-42, 2012 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma, Dixit: "Non-canonical inflammasome activation targets caspase-11." in: Nature, Vol. 479, Issue 7371, pp. 117-21, 2011

Bilder

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Immunohistochemistry-Paraffin: Caspase 11 Antibody (17D9) [ABIN2657624] - IHC-P analy...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse B cell. Image from ver...
Immunofluorescence (IF) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Immunocytochemistry/Immunofluorescence: Caspase 11 Antibody (17D9) [ABIN2657624] - Ca...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse liver extract was sepa...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - analysis of Caspase 11 in LP...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase-11 Antibody (17D9) [ABIN2657624] - Analysis of Caspase-11 in TH...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase-11 Antibody (17D9) - Casp11fl/fl and Casp11EC-/- mice (n = 3) ...