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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
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3.2589035 | ABIN3043186 | IHC (p) WB | Rabbit | IgG | AA 104-124, N-Term | Anmelden zum Anzeigen | Polyclonal | 2 | ||
3.2589035 | ABIN2787904 | WB | Rabbit | Middle Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN2787905 | WB | Rabbit | Middle Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN222883 | WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 1 | |||
3.2589035 | ABIN2705686 | IHC WB | Rabbit | Center | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN1536104 | ELISA WB | Rabbit | IgG | AA 62-111, Cleaved-Gln81 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
3.2589035 | ABIN1858247 | ICC IHC WB | Rabbit | IgG | AA 290-377 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
3.2589035 | ABIN967534 | WB | Mouse | IgG1, kappa | Anmelden zum Anzeigen | B25-1 | 2 | |||
3.2589035 | ABIN268673 | ELISA WB | Goat | Anmelden zum Anzeigen | Polyclonal | 1 | ||||
3.2589035 | ABIN615322 | IHC (p) WB | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN2477914 | IHC (p) WB | Rabbit | IgG | N-Term | Anmelden zum Anzeigen | Polyclonal | 3 | ||
3.2589035 | ABIN498677 | IHC (p) WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
3.2589035 | ABIN1077913 | ICC IHC WB | Rabbit | IgG | AA 78-265 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
3.2589035 | ABIN1326998 | ELISA WB | Mouse | IgG2a kappa | AA 1-377, full length | Anmelden zum Anzeigen | 7G7 | 0 | ||
3.2589035 | ABIN2465498 | ELISA WB | Goat | Internal Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN615323 | IHC (p) WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
3.2589035 | ABIN1030900 | IHC ELISA WB | Rabbit | Middle Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN1031297 | IHC ELISA WB | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
3.2589035 | ABIN4288124 | WB | Rabbit | IgG1 | N-Term | Anmelden zum Anzeigen | D44 | 0 | ||
3.2589035 | ABIN4288129 | WB | Mouse | IgG1 | Anmelden zum Anzeigen | 4A2 | 0 |
General |
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Antigen | Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper |
Reaktivität | Human, Maus Alternativen |
Wirt | Ratte Alternativen |
Klonalität (Klon) | |
Konjugat | Dieser Caspase 4 Antikörper ist unkonjugiert Alternativen |
Applikation |
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
Alternativen
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23 Publikationen vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-Caspase 4 AntikörperTarget Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder |
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Reinigung | Protein G purified |
Immunogen | A recombinant p30 subunit of mouse Caspase 11. [UniProt# P70343] |
Klon | 17D9 |
Isotyp | IgG2a |
Target Details Caspase 4Produktdetails anti-Caspase 4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | Caspase-11 (CASP4 Antibody Abstract) |
Hintergrund | Gene Symbol: CASP11 |
Molekulargewicht | Theoretical MW: 35-43 kDa |
Gen-ID | 12363 |
UniProt | P70343 |
Pathways | Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity |
AnwendungsinformationenProduktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben |
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Applikationshinweise | Western Blot 5 μg/mL, ELISA, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:100, Immunoprecipitation, Immunohistochemistry-Paraffin 1:100, Immunohistochemistry-Frozen 1:10-1:500, MicroarrayUse in immunprecipitation reported in scientific literature (PMID 10791975) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Kommentare |
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 1.0 mg/mL |
Buffer |
PBS Buffer contains: 0.02 % Sodium Azide |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid freeze-thaw cycles |
Lagerung | 4 °C,-20 °C |
Informationen zur Lagerung | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Referenzen für anti-Caspase 4 Antikörper (ABIN265762)Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Man, Karki, Briard, Burton, Gingras, Pelletier, Kanneganti: "Differential roles of caspase-1 and caspase-11 in infection and inflammation." in: Scientific reports, Vol. 7, pp. 45126, 2017 (Probematerial (Species): Mouse (Murine)). Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)). Cheng, Xiong, Ye, Hong, Di, Tsang, Gao, An, Mittal, Vogel, Miao, Rehman, Malik: "Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury." in: The Journal of clinical investigation, Vol. 127, Issue 11, pp. 4124-4135, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)). Chung, Vilaysane, Lau, Stahl, Morampudi, Bondzi-Simpson, Platnich, Bracey, French, Beck, Chun, Vallance, Muruve: "NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1331-46, 2016 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Kim, Bae, Ryu, Kwon, Oh, Kwon, Moon, Kim, Miyawaki, Lee, Shin, Kim, Kim, Ryter, Choi, Rhee, Ryu, Yoon: "SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages." in: Autophagy, Vol. 12, Issue 8, pp. 1272-91, 2016 Weitere Details: Western Blotting,Immunoprecipitation Klaska, Muckersie, Martin-Granados, Christofi, Forrester: "Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms." in: Immunology, Vol. 150, Issue 3, pp. 364-377, 2016 Youm, Nguyen, Grant, Goldberg, Bodogai, Kim, DAgostino, Planavsky, Lupfer, Kanneganti, Kang, Horvath, Fahmy, Crawford, Biragyn, Alnemri, Dixit: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." in: Nature medicine, Vol. 21, Issue 3, pp. 263-9, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting Aachoui, Kajiwara, Leaf, Mao, Ting, Coers, Aderem, Buxbaum, Miao: "Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium." in: Cell host & microbe, Vol. 18, Issue 3, pp. 320-32, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Shi, Zhao, Wang, Shi, Wang, Huang, Zhuang, Cai, Wang, Shao: "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death." in: Nature, Vol. 526, Issue 7575, pp. 660-5, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Kayagaki, Stowe, Lee, ORourke, Anderson, Warming, Cuellar, Haley, Roose-Girma, Phung, Liu, Lill, Li, Wu, Kummerfeld, Zhang, Lee, Snipas, Salvesen, Morris, Fitzgerald, Zhang, Bertram, Goodnow, Dixit: "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling." in: Nature, Vol. 526, Issue 7575, pp. 666-71, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Diabate, Munro, Garcia, Jacquel, Michel, Obba, Goncalves, Luci, Marchetti, Demon, Degos, Bechah, Mege, Lamkanfi, Auberger, Gorvel, Stuart, Landraud, Lemichez, Boyer: "Escherichia coli ?-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004732, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: ELISA Bonora, Wieckowsk, Chinopoulos, Kepp, Kroemer, Galluzzi, Pinton: "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition." in: Oncogene, Vol. 34, Issue 12, pp. 1608, 2015 Yuan, Syed, Panchal, Joo, Colonna, Brantly, Sadikot: "Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 15118-29, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Gurung, Anand, Malireddi, Vande Walle, Van Opdenbosch, Dillon, Weinlich, Green, Lamkanfi, Kanneganti: "FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1835-46, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Van Opdenbosch, Gurung, Vande Walle, Fossoul, Kanneganti, Lamkanfi: "Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation." in: Nature communications, Vol. 5, pp. 3209, 2014 Weitere Details: Western Blotting Case, Kohler, Lima, Strowig, de Zoete, Flavell, Zamboni, Roy: "Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1851-6, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Jin, Oda, Lai, Skalsky, Bethel, Shepherd, Kang, Liu, Sabouri-Ghomi, Cullen, Rajewsky, Xiao: "MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways." in: The EMBO journal, Vol. 32, Issue 17, pp. 2377-91, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: "An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1." in: The Biochemical journal, Vol. 443, Issue 2, pp. 355-9, 2012 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Sun, Wu, Hayashi, Peters, Tsuda, Inoue, Nakanishi: "Microglial cathepsin B contributes to the initiation of peripheral inflammation-induced chronic pain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 33, pp. 11330-42, 2012 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma, Dixit: "Non-canonical inflammasome activation targets caspase-11." in: Nature, Vol. 479, Issue 7371, pp. 117-21, 2011 |
BilderProduktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) zurück nach oben |
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Bilder des Herstellers |
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