anti-Human Caspase 4 Antikörper für Western Blotting

Recommended Caspase 4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • CASP13
  • CASP1
  • CASP4
  • Caspl
  • ich-3
  • Casp4
  • caspase 4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4
  • CASP4
  • Casp4
  • LOC100731032
Reaktivität
Human, Maus
205
103
42
22
3
1
1
Wirt
Ratte
202
27
20
18
7
Klonalität
Monoklonal
Konjugat
Dieser Caspase 4 Antikörper ist unkonjugiert
18
15
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
263
96
96
55
30
24
18
17
17
10
3
2
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
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Bilder

Produktnummer ABIN265762
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
19.252602 ABIN185284 ELISA WB Goat Internal Region Anmelden zum Anzeigen Polyclonal 1
17.056355 ABIN929107 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
13.803753 ABIN1858247 ICC IHC WB Rabbit IgG AA 290-377 Anmelden zum Anzeigen Polyclonal 0
13.803753 ABIN2899476 IF/ICC IHC IP WB Rabbit AA 290-377 Anmelden zum Anzeigen Polyclonal 0
13.803753 ABIN1326998 ELISA WB Mouse IgG2a kappa AA 1-377 Anmelden zum Anzeigen 7G7 0
13.252602 ABIN3183668 ELISA IHC WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN5621648 WB Mouse IgG1 N-Term Anmelden zum Anzeigen D44 0
13.252602 ABIN5619063 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN2135465 WB Mouse IgG1 N-Term Anmelden zum Anzeigen D44 0
13.252602 ABIN2135467 IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN5623087 WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN5623088 ICC IF IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN2135424 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN2135425 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13.252602 ABIN2135466 WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
12.303753 ABIN3043186 IHC (p) WB Rabbit IgG AA 104-124, N-Term Anmelden zum Anzeigen Polyclonal 2
10.803753 ABIN6260482 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10.803753 ABIN6260486 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10.803753 ABIN615322 IHC (p) WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
10.803753 ABIN5693193 ELISA IHC WB Rabbit AA 111-194 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper
Reaktivität Human, Maus
(205), (103), (42), (22), (3), (1), (1)
Wirt Ratte
(202), (27), (20), (18), (7)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Caspase 4 Antikörper ist unkonjugiert
(18), (15), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
(263), (96), (96), (55), (30), (24), (18), (17), (17), (10), (3), (2), (1), (1)
Pubmed 28 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 4 Antikörper

Target Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder
Reinigung Protein G purified
Immunogen A recombinant p30 subunit of mouse Caspase 11. [UniProt# P70343]
Klon 17D9
Isotyp IgG2a
Plasmids, Primers & others

Target Details Caspase 4

Produktdetails anti-Caspase 4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Antigen
Andere Bezeichnung Caspase-11 (CASP4 Antibody Abstract)
Hintergrund Gene Symbol: CASP11
Molekulargewicht Theoretical MW: 35-43 kDa
Gen-ID 12363
UniProt P70343
Pathways Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Applikations-hinweise Western Blot 5 μg/mL, ELISA, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:100, Immunoprecipitation, Immunohistochemistry-Paraffin 1:100, Immunohistochemistry-Frozen 1:10-1:500, MicroarrayUse in immunprecipitation reported in scientific literature (PMID 10791975) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Referenzen für anti-Caspase 4 Antikörper (ABIN265762) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-Caspase 4 Antikörper (ABIN265762)

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kolb, Phan, Borcherding, Liu, Yuan, Janowski, Xie, Markan, Li, Potthoff, Fuentes-Mattei, Ellies, Knudson, Lee, Yeung, Cassel, Sutterwala, Zhang: "Obesity-associated NLRC4 inflammasome activation drives breast cancer progression." in: Nature communications, Vol. 7, pp. 13007, 2018

Deigendesch, Zychlinsky, Meissner: "Copper Regulates the Canonical NLRP3 Inflammasome." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 5, pp. 1607-1617, 2018

Balakrishnan, Karki, Berwin, Yamamoto, Kanneganti: "Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa." in: Cell death discovery, Vol. 5, pp. 3, 2018

Man, Karki, Briard, Burton, Gingras, Pelletier, Kanneganti: "Differential roles of caspase-1 and caspase-11 in infection and inflammation." in: Scientific reports, Vol. 7, pp. 45126, 2017 (Probematerial (Species): Mouse (Murine)).

Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Cheng, Xiong, Ye, Hong, Di, Tsang, Gao, An, Mittal, Vogel, Miao, Rehman, Malik: "Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury." in: The Journal of clinical investigation, Vol. 127, Issue 11, pp. 4124-4135, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Kerur, Fukuda, Banerjee, Kim, Fu, Apicella, Varshney, Yasuma, Fowler, Baghdasaryan, Marion, Huang, Yasuma, Hirano, Serbulea, Ambati, Ambati, Kajiwara, Ambati, Hirahara, Bastos-Carvalho, Ogura et al.: "cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. ..." in: Nature medicine, Vol. 24, Issue 1, pp. 50-61, 2017 (Probematerial (Species): Human).

Man, Karki, Sasai, Place, Kesavardhana, Temirov, Frase, Zhu, Malireddi, Kuriakose, Peters, Neale, Brown, Yamamoto, Kanneganti: "IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes." in: Cell, Vol. 167, Issue 2, pp. 382-396.e17, 2017

Chung, Vilaysane, Lau, Stahl, Morampudi, Bondzi-Simpson, Platnich, Bracey, French, Beck, Chun, Vallance, Muruve: "NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1331-46, 2016 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kim, Bae, Ryu, Kwon, Oh, Kwon, Moon, Kim, Miyawaki, Lee, Shin, Kim, Kim, Ryter, Choi, Rhee, Ryu, Yoon: "SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages." in: Autophagy, Vol. 12, Issue 8, pp. 1272-91, 2016 Weitere Details: Western Blotting,Immunoprecipitation

Klaska, Muckersie, Martin-Granados, Christofi, Forrester: "Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms." in: Immunology, Vol. 150, Issue 3, pp. 364-377, 2016

Youm, Nguyen, Grant, Goldberg, Bodogai, Kim, DAgostino, Planavsky, Lupfer, Kanneganti, Kang, Horvath, Fahmy, Crawford, Biragyn, Alnemri, Dixit: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." in: Nature medicine, Vol. 21, Issue 3, pp. 263-9, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Aachoui, Kajiwara, Leaf, Mao, Ting, Coers, Aderem, Buxbaum, Miao: "Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium." in: Cell host & microbe, Vol. 18, Issue 3, pp. 320-32, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Shi, Zhao, Wang, Shi, Wang, Huang, Zhuang, Cai, Wang, Shao: "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death." in: Nature, Vol. 526, Issue 7575, pp. 660-5, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Kayagaki, Stowe, Lee, ORourke, Anderson, Warming, Cuellar, Haley, Roose-Girma, Phung, Liu, Lill, Li, Wu, Kummerfeld, Zhang, Lee, Snipas, Salvesen, Morris, Fitzgerald, Zhang, Bertram, Goodnow, Dixit: "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling." in: Nature, Vol. 526, Issue 7575, pp. 666-71, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Diabate, Munro, Garcia, Jacquel, Michel, Obba, Goncalves, Luci, Marchetti, Demon, Degos, Bechah, Mege, Lamkanfi, Auberger, Gorvel, Stuart, Landraud, Lemichez, Boyer: "Escherichia coli ?-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004732, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: ELISA

Bonora, Wieckowsk, Chinopoulos, Kepp, Kroemer, Galluzzi, Pinton: "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition." in: Oncogene, Vol. 34, Issue 12, pp. 1608, 2015

Demon, Kuchmiy, Fossoul, Zhu, Kanneganti, Lamkanfi: "Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis." in: Mucosal immunology, Vol. 7, Issue 6, pp. 1480-91, 2015

Yuan, Syed, Panchal, Joo, Colonna, Brantly, Sadikot: "Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 15118-29, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Gurung, Anand, Malireddi, Vande Walle, Van Opdenbosch, Dillon, Weinlich, Green, Lamkanfi, Kanneganti: "FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1835-46, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Bilder

Produktdetails anti-Caspase 4 Antikörper Target Details Caspase 4 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 4 Antikörper (ABIN265762) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Immunohistochemistry-Paraffin: Caspase 11 Antibody (17D9) [ABIN2657624] - IHC-P analy...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse B cell. Image from ver...
Immunofluorescence (IF) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Immunocytochemistry/Immunofluorescence: Caspase 11 Antibody (17D9) [ABIN2657624] - Ca...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse liver extract was sepa...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - analysis of Caspase 11 in LP...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase-11 Antibody (17D9) [ABIN2657624] - Analysis of Caspase-11 in TH...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN265762) Western Blot: Caspase-11 Antibody (17D9) - Casp11fl/fl and Casp11EC-/- mice (n = 3) ...