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Human Caspase 3 Protein expressed in Escherichia coli (E. coli) - ABIN413120
Basu, Lu, Sun, Moor, Akkaraju, Huang: Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals. in The Journal of biological chemistry 2002
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Mouse (Murine) Caspase 3 Protein expressed in Escherichia coli (E. coli) - ABIN413129
Pianu, Lefort, Thuiliere, Tabourier, Bartolini: The Aβ₁₋₄₂ peptide regulates microtubule stability independently of tau. in Journal of cell science 2014
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
, PARP cleavage protease
, SREBP cleavage activity 1
, caspase 3, apoptosis-related cysteine protease
, cysteine protease CPP32
, protein Yama
, caspase 3, apoptosis related cysteine protease
, Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease)
, Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease)
, yama protein
, Caspase-3-like protein
, caspase 3, apoptosis-related cysteine peptidase