anti-Human Caspase 1 Antikörper für Western Blotting

Recommended Caspase 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 1 (CASP1) Antikörper
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
Epitop
AA 135-152, N-Term
35
16
12
11
10
9
9
9
7
7
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
258
96
75
8
2
2
2
1
1
1
1
1
1
Wirt
Kaninchen
249
37
8
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 1 Antikörper ist unkonjugiert
23
16
8
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
266
161
118
75
32
26
18
15
7
5
3
3
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN3043221
$ 280.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
22.575909 ABIN2855008 ICC IF IHC (p) WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
21.297693 ABIN3044293 IHC (p) WB Rabbit IgG AA 249-262, C-Term Anmelden zum Anzeigen Polyclonal 21
18.297693 ABIN560170 IHC (p) ELISA WB Mouse IgG2a kappa AA 1-100, partial Anmelden zum Anzeigen 3D2 2
16.797693 ABIN393212 ELISA IHC WB Mouse IgG2a kappa AA 1-100 Anmelden zum Anzeigen 3D2 5
16.575909 ABIN3183664 ELISA IHC WB Rabbit IgG Ser197 Anmelden zum Anzeigen Polyclonal 0
16.575909 ABIN3181758 ELISA IHC WB Rabbit IgG Asp210, cleaved Anmelden zum Anzeigen Polyclonal 0
16.575909 ABIN3021171 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
16.575909 ABIN929105 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN4901137 ELISA WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN3181774 ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN3182631 ELISA IHC WB Rabbit IgG pSer376 Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN5617521 ELISA IHC WB Rabbit IgG Ser376 Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN5619047 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN5619046 IHC IP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN5619044 ICC IF WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN5619048 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN2135441 IHC ELISA WB Rabbit IgG Asp210 Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN2135444 IHC ELISA WB Rabbit IgG pSer376 Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN2135439 IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN2135443 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Caspase 1 (CASP1) Antikörper
Epitop AA 135-152, N-Term
(35), (16), (12), (11), (10), (9), (9), (9), (7), (7), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(258), (96), (75), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(249), (37), (8), (2)
Klonalität
Polyklonal
Konjugat Dieser Caspase 1 Antikörper ist unkonjugiert
(23), (16), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(266), (161), (118), (75), (32), (26), (18), (15), (7), (5), (3), (3), (1)
Pubmed 21 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 1 Antikörper

Target Details Caspase 1 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 1 Antikörper (ABIN3043221) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Caspase-1(CASP1) detection. Tested with WB, IHC-P in Human.
Sequenz CSLEEAQRIW KQKSAEIY
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Caspase-1(CASP1) detection. Tested with WB, IHC-P in Human.
Gene Name: caspase 1, apoptosis-related cysteine peptidase
Protein Name: Caspase-1(CASP-1)
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human CASP1(135-152aa CSLEEAQRIWKQKSAEIY).
Isotyp IgG
Plasmids, Primers & others

Target Details Caspase 1

Produktdetails anti-Caspase 1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Caspase 1 Antikörper (ABIN3043221) Bilder zurück nach oben
Antigen
Andere Bezeichnung CASP1 (CASP1 Antibody Abstract)
Hintergrund Caspase 1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL18, and IL33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase1 gene consists of 10 exons spanning at least 10.6 kb. The Caspase 1 gene is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas, by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chromosomes. Caspase 1 has been shown to induce cell necrosis or pyroptosis and may function in various developmental stages.

Synonyms: CASP 1 antibody|CASP-1 antibody|CASP1 antibody|Caspase 1 apoptosis related cysteine peptidase antibody|Caspase 1 apoptosis related cysteine protease antibody|Caspase-1 subunit p20 antibody|Caspase1 antibody|ICE antibody|IL 1 beta converting enzyme antibody|IL 1BC antibody|IL-1 beta-converting enzyme antibody|IL-1BC antibody|IL1 beta converting enzyme antibody|IL1B convertase antibody|IL1BC antibody|IL1BCE antibody|Interleukin 1 beta convertase antibody|Interleukin 1 beta convertase precursor antibody|Interleukin 1 beta converting enzyme antibody|Interleukin 1B converting enzyme antibody|Interleukin-1 beta convertase antibody|Interleukin-1 beta-converting enzyme antibody|P45 antibody
UniProt P29466
Pathways Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Handhabung Referenzen für anti-Caspase 1 Antikörper (ABIN3043221) Bilder zurück nach oben
Applikations-hinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Anwendungsinformationen Referenzen für anti-Caspase 1 Antikörper (ABIN3043221) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungs-mittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months

Referenzen für anti-Caspase 1 Antikörper (ABIN3043221)

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Xu, Liu, Zhang, Wang, Wang, Yang, Huo, Sun: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, 2015

Lu, Yuan, Ou, Cai, Wang, Sun, Zhang: "Autophagy and apoptosis during adult adipose-derived stromal cells differentiation into neuron-like cells in vitro." in: Neural regeneration research, Vol. 7, Issue 16, pp. 1205-12, 2015

Chen, Peng, Rowat, Gao, Zhang, Wang, Zhang, Wang, Qu: "The effect of concentration and duration of normobaric oxygen in reducing caspase-3 and -9 expression in a rat-model of focal cerebral ischaemia." in: Brain research, Vol. 1618, pp. 205-11, 2015

Ji, Yan, Li, Lai, Liu: "Therapeutic effects of intrathecal versus intravenous monosialoganglioside against bupivacaine-induced spinal neurotoxicity in rats." in: Biomedicine & pharmacotherapy = Biome?decine & pharmacothe?rapie, Vol. 69, pp. 311-6, 2015

Wu, Wang, Hou: "Alpha B-crystallin improved survival of retinal ganglion cells in a rat model of acute ocular hypertension." in: Neural regeneration research, Vol. 7, Issue 19, pp. 1493-7, 2015

Wang, Qu, Zhang, Zhang: "Testosterone suppresses ventricular remodeling and improves left ventricular function in rats following myocardial infarction." in: Experimental and therapeutic medicine, Vol. 9, Issue 4, pp. 1283-1291, 2015

Liu, Chen, Wang, Yang, Xue, Zhu: "Msi1 confers resistance to TRAIL by activating ERK in liver cancer cells." in: FEBS letters, Vol. 589, Issue 8, pp. 897-903, 2015

Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." in: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, 2015

Zhang, Yan, Hu, Zhuang, Yu, Hang: "Increased Expression of NLRP3 Inflammasome in Wall of Ruptured and Unruptured Human Cerebral Aneurysms: Preliminary Results." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 24, Issue 5, pp. 972-9, 2015

Huang, Huang, Xiao, Yang, Lin, Diao: "Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-?B signaling pathway." in: Biomedicine & pharmacotherapy = Biome?decine & pharmacothe?rapie, Vol. 68, Issue 4, pp. 455-61, 2014

Mao, Song, Li, Lv, Zhao, Li, Feng, Chen: "8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury." in: Neural regeneration research, Vol. 8, Issue 2, pp. 133-42, 2014

Dai, Li, Tang, Li, Xiao: "Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways." in: Antimicrobial agents and chemotherapy, Vol. 58, Issue 7, pp. 4075-85, 2014

Yuan, Sun, Ou, Wang, Zhang, Deng, Wu, Zhang: "Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes." in: Neural regeneration research, Vol. 9, Issue 8, pp. 837-44, 2014

Chen, Dang, Wang, Tang, Liu, Wu: "The in vitro and in vivo anti-tumor effects of MTX-Fe3O 4-PLLA-PEG-PLLA microspheres prepared by suspension-enhanced dispersion by supercritical CO2." in: Science China. Life sciences, Vol. 57, Issue 7, pp. 698-709, 2014

Shu, Yu, Zhang, Liu, Wu, Zang, Yang, Zhou, Yin: "Expression of TRPV1 in cortical lesions from patients with tuberous sclerosis complex and focal cortical dysplasia type IIb." in: Brain & development, Vol. 35, Issue 3, pp. 252-60, 2013

Li, Peng, Song, Liang, Mei, Fang: "Electro-acupuncture combined with transcranial magnetic stimulation improves learning and memory function of rats with cerebral infarction by inhibiting neuron cell apoptosis." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 32, Issue 5, pp. 746-9, 2012

Li, Li, Huang, Kan, Wang, Wu, Yin, Yao: "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." in: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, 2011

Fu, Zhao, Wu, Wu, Xu, Liu, Tong: "Therapeutic mechanisms of Tongmai Dasheng Tablet on tripterygium glycosides induced rat model for premature ovarian failure." in: Journal of ethnopharmacology, Vol. 139, Issue 1, pp. 26-33, 2011

Zhao, Wu, Wu, Jia, Gao, Yan, Wang: "Introduction of hypoxia-targeting p53 fusion protein for the selective therapy of non-small cell lung cancer." in: Cancer biology & therapy, Vol. 11, Issue 1, pp. 95-107, 2011

Ding, Zou, Li, Tian, Abdelalim, Du, She, Wang, Tan, Wang, Chen, Lv, Chang: "Study of histopathological and molecular changes of rat kidney under simulated weightlessness and resistance training protective effect." in: PLoS ONE, Vol. 6, Issue 5, pp. e20008, 2011

Bilder

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Anwendungsinformationen Handhabung Referenzen für anti-Caspase 1 Antikörper (ABIN3043221) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibody (ABIN3043221) Anti-Caspase-1(P20) antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: RAJ...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibody (ABIN3043221) Anti-Caspase-1(P20) antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibody (ABIN3043221) Anti-Caspase-1(P20) antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane ...