anti-Ratte (Rattus) BCL2L1 Antikörper für Flow Cytometry

Recommended BCL2L1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
BCL2-Like 1 (BCL2L1) Antikörper
  • BCL-XL/S
  • BCL2L
  • BCLX
  • BCLXL
  • BCLXS
  • Bcl-X
  • PPP1R52
  • bcl-xL
  • bcl-xS
  • Bcl(X)L
  • Bcl-XL
  • Bcl-Xs
  • Bcl2l
  • BclX
  • bcl-x
  • Bcl-xl
  • Bclx
  • bcl-X
  • Bcl-xL
  • BCL-XL
  • BCL2L1
  • bcl-XL
  • bcl-x(l)
  • bcl-xl/s
  • bcl-xs
  • bcl2l
  • bclx
  • bclxl
  • xR11
  • bcl-xl
  • blp1
  • cb1021
  • zfBLP1
  • BCL2 like 1
  • BCL2-like 1
  • Bcl2-like 1
  • BCL2-like 1 L homeolog
  • bcl2-like 1
  • BCL2L1
  • Bcl2l1
  • bcl2l1
  • bcl2l1.L
Reaktivität
Human, Maus, Ratte (Rattus)
528
398
374
204
32
17
15
13
12
10
8
5
4
4
2
1
Wirt
Maus
294
266
3
2
Klonalität
Monoklonal
Konjugat
Dieser BCL2L1 Antikörper ist unkonjugiert
29
18
15
12
9
9
7
7
6
6
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
443
217
214
196
185
148
107
93
87
64
27
10
8
7
5
3
2
2
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN371611
$ 467.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN371609 FACS Biotin Mouse IgG3 Anmelden zum Anzeigen 7B2-5 15
1 ABIN371610 FACS FITC Mouse IgG3 Anmelden zum Anzeigen 7B2-5 15
1 ABIN4283652 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Anmelden zum Anzeigen BX006 0
1 ABIN386441 FACS IF IHC IHC (p) Mouse IgG2a AA 3-14 Anmelden zum Anzeigen 2H12 0
1 ABIN6175438 FACS IF IHC (f) WB CF®405S Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175440 FACS IF IHC (f) WB CF405M Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175442 FACS IF IHC (f) WB CF®640R Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175444 FACS IF IHC (f) WB CF®543 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175446 FACS IF IHC (f) WB CF®647 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175448 FACS IF IHC (f) WB CF®555 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175380 FACS IF IHC (f) WB CF®680 Mouse IgG2a AA 3-14 Anmelden zum Anzeigen BX006 0
1 ABIN6175382 FACS IF IHC (f) WB CF®680R Mouse IgG2a AA 3-14 Anmelden zum Anzeigen BX006 0
1 ABIN6175384 FACS IF IHC (f) WB CF®488A Mouse IgG2a AA 3-14 Anmelden zum Anzeigen BX006 0
1 ABIN6175386 FACS IF IHC (f) WB CF®594 Mouse IgG2a AA 3-14 Anmelden zum Anzeigen BX006 0
1 ABIN6175452 FACS IF IHC (f) WB CF®568 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175454 FACS IF IHC (f) WB CF®770 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175456 FACS IF IHC (f) WB CF®680 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175458 FACS IF IHC (f) WB CF®680R Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175460 FACS IF IHC (f) WB CF®488A Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0
1 ABIN6175462 FACS IF IHC (f) WB CF®594 Mouse IgG AA 3-14 Anmelden zum Anzeigen BX006 2H12 0

General

Antigen BCL2-Like 1 (BCL2L1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(528), (398), (374), (204), (32), (17), (15), (13), (12), (10), (8), (5), (4), (4), (2), (1)
Wirt Maus
(294), (266), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser BCL2L1 Antikörper ist unkonjugiert
(29), (18), (15), (12), (9), (9), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(443), (217), (214), (196), (185), (148), (107), (93), (87), (64), (27), (10), (8), (7), (5), (3), (2), (2), (1)
Pubmed 15 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-BCL2L1 Antikörper

Target Details BCL2L1 Anwendungsinformationen Handhabung Referenzen für anti-BCL2L1 Antikörper (ABIN371611) Bilder
Spezifität This antibody recognizes Bcl-xL.
Produktmerkmale Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
Reinigung Purified
Immunogen Recombinant Bcl-xS.
Klon 7B2-5
Isotyp IgG3
Plasmids, Primers & others

Target Details BCL2L1

Produktdetails anti-BCL2L1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-BCL2L1 Antikörper (ABIN371611) Bilder zurück nach oben
Antigen
Andere Bezeichnung Bcl-2-Like 1 (BCL2L1 Antibody Abstract)
Hintergrund Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. (Ref.1) It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. (Ref.2) Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis (Ref.3,4) while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. (Ref.5-8) Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. (Ref.9-13) In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2. (Ref.5,14) Other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity. (Ref.15,16)Synonyms: BCL2L, BCL2L1, BCLX, Bcl-2-like protein 1, Bcl-x, Bcl2-L-1, bcl-xL, bcl-xS
UniProt Q07817
Pathways Apoptose, Negative Regulation of intrinsic apoptotic Signaling

Anwendungsinformationen

Produktdetails anti-BCL2L1 Antikörper Target Details BCL2L1 Handhabung Referenzen für anti-BCL2L1 Antikörper (ABIN371611) Bilder zurück nach oben
Applikations-hinweise Flow Cytometry: < / = 3 μg/10^6 cells. Western Blot: < / = 0.5 μg/mL. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-BCL2L1 Antikörper Target Details BCL2L1 Anwendungsinformationen Referenzen für anti-BCL2L1 Antikörper (ABIN371611) Bilder zurück nach oben
Konzentration 0.1 mg/mL
Buffer 100 mM Borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months

Referenzen für anti-BCL2L1 Antikörper (ABIN371611)

Produktdetails anti-BCL2L1 Antikörper Target Details BCL2L1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Gottschalk, Boise, Oltvai, Accavitti, Korsmeyer, Quintáns, Thompson: "The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." in: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, 2006

Nuñez, Clarke: "The Bcl-2 family of proteins: regulators of cell death and survival." in: Trends in cell biology, Vol. 4, Issue 11, pp. 399-403, 2004

Cheng, Levine, Boise, Thompson, Hardwick: "Bax-independent inhibition of apoptosis by Bcl-XL." in: Nature, Vol. 379, Issue 6565, pp. 554-6, 1996

Cory: "Regulation of lymphocyte survival by the bcl-2 gene family." in: Annual review of immunology, Vol. 13, pp. 513-43, 1995

Farrow, White, Martinou, Raven, Pun, Grinham, Martinou, Brown: "Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K." in: Nature, Vol. 374, Issue 6524, pp. 731-3, 1995

Chittenden, Harrington, OConnor, Flemington, Lutz, Evan, Guild: "Induction of apoptosis by the Bcl-2 homologue Bak." in: Nature, Vol. 374, Issue 6524, pp. 733-6, 1995

Kiefer, Brauer, Powers, Wu, Umansky, Tomei, Barr: "Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak." in: Nature, Vol. 374, Issue 6524, pp. 736-9, 1995

Dole, Jasty, Cooper, Thompson, Nuñez, Castle: "Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis." in: Cancer research, Vol. 55, Issue 12, pp. 2576-82, 1995

Shimizu, Eguchi, Kosaka, Kamiike, Matsuda, Tsujimoto: "Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL." in: Nature, Vol. 374, Issue 6525, pp. 811-3, 1995

González-García, García, Ding, OShea, Boise, Thompson, Núñez: "bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 10, pp. 4304-8, 1995

Yin, Oltvai, Korsmeyer: "BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax." in: Nature, Vol. 369, Issue 6478, pp. 321-3, 1994

Gottschalk, Boise, Thompson, Quintáns: "Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 15, pp. 7350-4, 1994

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993

Boise, González-García, Postema, Ding, Lindsten, Turka, Mao, Nuñez, Thompson: "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death." in: Cell, Vol. 74, Issue 4, pp. 597-608, 1993

Cohen: "Programmed cell death in the immune system." in: Advances in immunology, Vol. 50, pp. 55-85, 1991

Bilder

Produktdetails anti-BCL2L1 Antikörper Target Details BCL2L1 Anwendungsinformationen Handhabung Referenzen für anti-BCL2L1 Antikörper (ABIN371611) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-BCL2-Like 1 (BCL2L1) antibody (ABIN371611) anti-BCL2-Like 1 (BCL2L1) antibody