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Cdc2, p34 (C-Term) Antikörper

Reaktivität: Human IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN97117
  • Target
    Cdc2, p34
    Bindungsspezifität
    C-Term
    Reaktivität
    • 1
    • 1
    Human
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Unkonjugiert
    Applikation
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by Refractometry
    Immunogen
    cdc2 peptide corresponding to the of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
  • Applikationshinweise
    This antibody is suitable for immunoblotting, immunohistochemistry immuno-precipitation (as active kinase), and immunoblotting.  HeLa cell lysate or human colon carcinoma is suggested as a positive control for immunoblotting.  LEP fibroblast cell lysate is suggested as a negative control. This product is suitable for the detection by immunoblot of human, rat and mouse cdc2. For immunohistochemistry use paraffin embedded tissue.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    85 mg/mL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Cdc2, p34
    Hintergrund
    P34 cdc2 is a serine-threonine protein kinase of 34,000 daltons that complexes with cyclin to form maturation promoting factor (MPF).  The inactive form of the protein is phosphorylated at threonine (T) and tyrosine (Y) residues.  In humans the phosphor-ylation appears to be performed by p60src.  The active form of the protein is dephosphorylated and it functions by phosphor-ylating a number of proteins.  The phosphorylation activity is coupled to the entry into the M-phase of the cell.  p34 cdc2 protein must be associated with a normal cyclin protein for the M-phase to be completed normally.  Association with deletion mutants of cyclin halts the M-phase before it is completed.
    Synonyms: Cell Divsion Cycle 2 Protein antibody, Cyclin Dependent Kinase 1 antibody, DKFZp686L20222 antibody, MGC111195 antibody, p34 antibody, p34 Cdk1 antibody, p34 protein kinase antibody
    Gen-ID
    983
    UniProt
    P06493
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