DKK1 Antikörper

Produktnummer ABIN969085

Produktdetails anti-DKK1 Antikörper

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DKK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of DKK1 expressed in E. coli.

Klon: 2H2

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-DKK1 Antikörper (ABIN969085)

Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: "Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling." in: Developmental cell, Vol. 15, Issue 1, pp. 37-48, (2008) (PubMed).

Qiao, Xu, Zhao, Ye, Zhang: "Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling." in: Cancer letters, Vol. 269, Issue 1, pp. 67-77, (2008) (PubMed).

Details zu DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1 (DKK1 Produkte)

Synonyme: DKK-1 antikoerper, SK antikoerper, AI414495 antikoerper, SGY antikoerper, SGY-1 antikoerper, SGY1 antikoerper, Soggy antikoerper, mSgy antikoerper, dkk1 antikoerper, dkk antikoerper, dkk-1 antikoerper, xdkk1 antikoerper, Xdkk-1 antikoerper, Dickkopf1 antikoerper, dickkopf-1 antikoerper, mdkk-1 antikoerper, dkk1-A antikoerper, dickkopf WNT signaling pathway inhibitor 1 antikoerper, dickkopf like acrosomal protein 1 antikoerper, dickkopf-related protein 1 antikoerper, dickkopf-like 1 antikoerper, dickkopf WNT signaling pathway inhibitor 1b antikoerper, dickkopf protein antikoerper, dickkopf WNT signaling pathway inhibitor 1 S homeolog antikoerper, DKK1 antikoerper, Dkk1 antikoerper, DKKL1 antikoerper, LOC100228789 antikoerper, Dkkl1 antikoerper, dkk1b antikoerper, dkk1 antikoerper, dickkopf antikoerper, dkk1.S antikoerper

Hintergrund:

Description: DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Aliases: SK, DKK-1,

Molekulargewicht: 28.7 kDa

Gen-ID: 22943

HGNC: 22943

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation