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Bcl-2 Antikörper

Name: Bcl-2 Antikörper
Brand: antibodies-online
SKU: ABIN968975
Price: 562.94 EUR
Availability: InStock

BCL2 Reaktivität: Human, Maus IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 8-00E-12 unconjugated

Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human brain tissues (right) using BCL-2 mouse mAb with DAB staining.

IHC

Immunofluorescence analysis of NIH/3T3 cells using BCL-2 mouse mAb (green).

Flow cytometric analysis of 3T3L1 cells using BCL-2 mouse mAb (green) and negative control (purple).

FACS

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN968975

Datenblatt (PDF)

Target Alle Bcl-2 (BCL2) Antikörper anzeigen

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
Reaktivität
445

190

185

38

34

22

22

19

17

16

12

5

5

1

1

1
Human, Maus
Wirt
349

123

6

2

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
346

136
Monoklonal
Konjugat
215

34

33

25

25

14

14

13

11

11

11

11

9

9

9

9

9

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser Bcl-2 Antikörper ist unkonjugiert
Applikation
389

200

167

114

107

103

92

74

64

32

29

25

18

8

8

8

5

4

3

2

1

1

1

1

1

1
Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Immunogen

Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.

Klon

8-00E-12

Isotyp

IgG1

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anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 81-131) antibody
BCL2 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibody
BCL2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Huhn, Bakterien WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB04684 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibody
BCL2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reaktivität: Human WB, FACS, IHC (p), IP, ICC, IHC (fro) Wirt: Maus Monoclonal Bcl-2-100 unconjugated

Applikationshinweise

ELISA: 1:10000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Choi, Feng, Yoon: "FKBP38 protects Bcl-2 from caspase-dependent degradation." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9770-9, (2010) (PubMed).

Munda, Hajdinjak, Kavalar, Stiblar Martincic: "p53, Bcl-2 and AgNOR tissue markers: model approach in predicting prostate cancer characteristics." in: The Journal of international medical research, Vol. 37, Issue 6, pp. 1868-76, (2010) (PubMed).

Murphy, Green, Adams, Squire, Kuo, McKay: "Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States." in: American journal of pharmaceutical education, Vol. 74, Issue 1, pp. 7, (2010) (PubMed).
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Andere Bezeichnung

BCL-2 (BCL2 Produkte)

Synonyme

Bcl-2 antikoerper, PPP1R50 antikoerper, bcl-2 antikoerper, AW986256 antikoerper, C430015F12Rik antikoerper, D630044D05Rik antikoerper, D830018M01Rik antikoerper, BCL-2 antikoerper, Bcl2 antikoerper, BCL2, apoptosis regulator antikoerper, B cell leukemia/lymphoma 2 antikoerper, B-cell CLL/lymphoma 2a antikoerper, B-cell CLL/lymphoma 2 protein antikoerper, BCL2 antikoerper, Bcl2 antikoerper, bcl2a antikoerper, BCL-2 antikoerper

Hintergrund

Description: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Tissue specificity: Expressed in a variety of tissues.
Aliases: Bcl-2, BCL2

Molekulargewicht

26 kDa

Gen-ID

596

HGNC

596

Pathways

MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling