VAV1 Antikörper (Vav 1 Oncogene) (pTyr174)

Details for Product anti-VAV1 Antibody No. ABIN967241
Antigen
Epitop
pTyr174
40
17
16
9
9
7
7
6
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
154
85
68
3
3
2
1
1
1
1
Wirt
Kaninchen
142
13
Konjugat
Dieser VAV1 Antikörper ist unkonjugiert
6
4
4
4
4
4
4
2
2
2
2
2
Applikation
Western Blotting (WB)
123
73
32
12
10
10
5
3
1
1
Optionen
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Vav around the phosphorylation site of tyrosine 174 (E-I-YP-E-D).
Spezifität Vav (phospho-Tyr174) antibody detects endogenous levels of Vav only when phosphorylated at tyrosine 174.
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Antigen
Andere Bezeichnung Vav (VAV1 Antibody Abstract)
Pathways T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events
Applikations-hinweise WB: 1:500~1:1000.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Produkt verwendet in: Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, 2005 (PubMed).

Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, 2000 (PubMed).