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Factor VIII Antikörper

F8 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5E9B2 unconjugated
Produktnummer ABIN966113
  • Target Alle Factor VIII (F8) Antikörper anzeigen
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Reaktivität
    • 95
    • 59
    • 30
    • 17
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 88
    • 21
    • 4
    • 2
    Maus
    Klonalität
    • 95
    • 20
    Monoklonal
    Konjugat
    • 50
    • 15
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Factor VIII Antikörper ist unkonjugiert
    Applikation
    • 55
    • 42
    • 39
    • 39
    • 24
    • 11
    • 10
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of F8 expressed in E. Coli.
    Klon
    5E9B2
    Isotyp
    IgG1
    Top Product
    Discover our top product F8 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Shovlin, Sulaiman, Govani, Jackson, Begbie: "Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism." in: Thrombosis and haemostasis, Vol. 98, Issue 5, pp. 1031-9, (2007) (PubMed).

  • Target
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Andere Bezeichnung
    F8 (F8 Produkte)
    Synonyme
    fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper
    Hintergrund
    F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
    Synonyms: AHF, F8B, F8C, HEMA, FVIII
    Gen-ID
    2157
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