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MUC1 Antikörper (DTRP (Asp-Thr-Arg-Pro))

MUC1 Reaktivität: Human IHC (p), IHC (fro) Wirt: Maus Monoclonal B24-1 (GP1-4) unconjugated
Produktnummer ABIN966067
  • Target Alle MUC1 Antikörper anzeigen
    MUC1 (Mucin 1 (MUC1))
    Bindungsspezifität
    • 26
    • 19
    • 16
    • 16
    • 12
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    DTRP (Asp-Thr-Arg-Pro)
    Reaktivität
    • 275
    • 58
    • 30
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 198
    • 90
    • 2
    • 1
    Maus
    Klonalität
    • 176
    • 110
    • 5
    Monoklonal
    Konjugat
    • 147
    • 26
    • 16
    • 12
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MUC1 Antikörper ist unkonjugiert
    Applikation
    • 142
    • 138
    • 103
    • 86
    • 75
    • 47
    • 26
    • 25
    • 24
    • 20
    • 18
    • 14
    • 13
    • 13
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    Concentrated.
    Immunogen
    Human Milk Fat Globule Membranes
    Klon
    B24-1 (GP1-4)
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MUC1 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry: (Paraffin/Frozen): 1:50.
    Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
    Kommentare

    Cellular Localization: Cell Membrane, Cytoplasmic.
    Recommended Positive Control: Breast Carcinoma

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.3 mg/ml.
    Buffer
    20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Hilkens, Ligtenberg, Vos, Litvinov: "Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).

    Hilkens, Buijs, Hilgers, Hageman, Calafat, Sonnenberg, van der Valk: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).

  • Target
    MUC1 (Mucin 1 (MUC1))
    Andere Bezeichnung
    EMA (MUC1 Produkte)
    Synonyme
    CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
    Hintergrund
    Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
    Molekulargewicht
    265-400 kDa
    Gen-ID
    4582
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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