EIF4E Antikörper

Produktnummer ABIN966052

Produktdetails anti-EIF4E Antikörper

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EIF4E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human EIF4E expressed in E. Coli.

Klon: 5D11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-EIF4E Antikörper (ABIN966052)

Slepenkov, Korneeva, Rhoads: "Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25227-37, (2008) (PubMed).

Details zu EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Andere Bezeichnung: EIF4E (EIF4E Produkte)

Synonyme: AUTS19 antikoerper, CBP antikoerper, EIF4E1 antikoerper, EIF4EL1 antikoerper, EIF4F antikoerper, eif4e-1 antikoerper, zgc:86680 antikoerper, EG668879 antikoerper, Eif4e-ps antikoerper, If4e antikoerper, eIF-4E antikoerper, 0260/09 antikoerper, 0587/11 antikoerper, 0589/11 antikoerper, 0919/12 antikoerper, 1004/13 antikoerper, 2 antikoerper, 7238 antikoerper, CG4035 antikoerper, CT13384 antikoerper, CT39424 antikoerper, CT39426 antikoerper, D-eIF4E antikoerper, Dmel\\CG4035 antikoerper, Eif4E antikoerper, Eif4e antikoerper, IF4E antikoerper, dEif4e antikoerper, deIF-4E antikoerper, deIF4E antikoerper, eIF 4E antikoerper, eIF-4E1 antikoerper, eIF-4E2 antikoerper, eIF-4EII antikoerper, eIF-4e antikoerper, eIF4E antikoerper, eIF4E-1 antikoerper, eIF4E-1/2 antikoerper, eIF4E-2 antikoerper, eIF4E1 antikoerper, eIF4EI antikoerper, eIF4e antikoerper, eif-4E antikoerper, eif-4e antikoerper, eif4e antikoerper, l(3)07238 antikoerper, l(3)67Af antikoerper, l(3)S025007 antikoerper, l(3)S026009 antikoerper, l(3)S058711 antikoerper, l(3)S091912 antikoerper, cbp antikoerper, eif4f antikoerper, eif4e1 antikoerper, eif4el1 antikoerper, EIF-4E antikoerper, zgc:101581 antikoerper, eukaryotic translation initiation factor 4E antikoerper, eukaryotic translation initiation factor 4ea antikoerper, Eukaryotic initiation factor 4E antikoerper, eucaryotic initiation factor 6 antikoerper, eukaryotic translation initiation factor 4E L homeolog antikoerper, eukaryotic translation initiation factor 4E family member 1B S homeolog antikoerper, translation initiation factor eIF4E antikoerper, eukaryotic translation initiation factor 4eb antikoerper, EIF4E antikoerper, eif4ea antikoerper, Eif4e antikoerper, eIF-4E antikoerper, eif6 antikoerper, eif4e antikoerper, eif4e.L antikoerper, eif4e1b.S antikoerper, LOC100533326 antikoerper, eif4eb antikoerper

Hintergrund: EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Synonyms: CBP, EIF4F, EIF4E1, EIF4EL1, MGC111573, EIF4E

Molekulargewicht: 25kDa

Gen-ID: 1977

Pathways: BCR Signaling