CST3 Antikörper

Produktnummer ABIN965940

Produktdetails anti-CST3 Antikörper

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CST3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CST3 expressed in E. Coli.

Klon: 5H2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-CST3 Antikörper (ABIN965940)

Helisalmi, Väkevä, Hiltunen, Soininen: "Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease." in: Dementia and geriatric cognitive disorders, Vol. 27, Issue 4, pp. 318-21, (2009) (PubMed).

Aubin, Labelle, Chevrefils, Desroches, Clin, Eng: "Preoperative planning simulator for spinal deformity surgeries." in: Spine, Vol. 33, Issue 20, pp. 2143-52, (2008) (PubMed).

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: CST3 (CST3 Produkte)

Synonyme: armd11 antikoerper, fb51d07 antikoerper, wu:fb24g06 antikoerper, wu:fb51d07 antikoerper, wu:fc55f03 antikoerper, zgc:136227 antikoerper, ARMD11 antikoerper, CysC antikoerper, CYSC antikoerper, cystatin C antikoerper, cystatin C L homeolog antikoerper, cystatin C (amyloid angiopathy and cerebral hemorrhage) antikoerper, cystatin 3 antikoerper, CST3 antikoerper, cst3.L antikoerper, cst3 antikoerper, cystatin 3 antikoerper, Cst3 antikoerper

Hintergrund: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.
Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Synonyms: ARMD11, MGC117328, CST3

Molekulargewicht: 42kDa

Gen-ID: 1471