BPTF Antikörper

Produktnummer ABIN965692

Produktdetails anti-BPTF Antikörper

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BPTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human BLNK expressed in E. Coli.

Klon: 2F10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications. Determinine optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-BPTF Antikörper (ABIN965692)

Imamura, Oda, Katahira, Bundo, Pike, Ratcliffe, Kitamura: "BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9804-13, (2009) (PubMed).

Kamino, Futamura, Nakamura, Kitamura, Kabu, Arakawa: "B-cell linker protein prevents aneuploidy by inhibiting cytokinesis." in: Cancer science, Vol. 99, Issue 12, pp. 2444-54, (2008) (PubMed).

Details zu BPTF

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Andere Bezeichnung: BPTF (BPTF Produkte)

Synonyme: FAC1 antikoerper, FALZ antikoerper, NURF301 antikoerper, 9430093H17Rik antikoerper, Falz antikoerper, BPTF antikoerper, bromodomain PHD finger transcription factor antikoerper, nucleosome-remodeling factor subunit NURF301 antikoerper, fetal alzheimer antigen, falz antikoerper, BPTF antikoerper, Bptf antikoerper, LOC5576547 antikoerper, CpipJ_CPIJ011285 antikoerper, bptf antikoerper

Hintergrund: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: AGM4, BASH, LY57, SLP65, BLNKS, SLP-65, MGC111051

Molekulargewicht: 68kDa

Gen-ID: 2186