ATF2 Antikörper (Activating Transcription Factor 2) (pThr53)

Details for Product anti-ATF2 Antibody No. ABIN965608, Anbieter: Anmelden zum Anzeigen
Antigen
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CHN1
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • activating transcription factor 2
  • Activating transcription factor-2
  • activating transcription factor 2 S homeolog
  • ATF2
  • Atf-2
  • Atf2
  • atf2.S
  • atf2
Epitop
pThr53, pThr71
81
51
39
35
35
35
35
34
34
33
32
25
21
20
15
14
13
13
11
10
10
9
8
7
7
6
6
6
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
692
421
382
30
21
16
14
12
10
10
5
5
2
2
2
1
1
Wirt
Kaninchen
615
56
19
4
Konjugat
Dieser ATF2 Antikörper ist unkonjugiert
16
15
15
10
10
9
9
9
9
9
9
9
9
9
7
7
6
3
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC)
502
330
198
134
133
118
85
24
22
12
11
7
7
3
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 71 or 53 (T-P-TP-P-T).
Spezifität ATF-2 (phospho-Thr71 or 53) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 71 or 53.
Plasmids, Primers & others Plasmide, Primers & weitere ATF2 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung ATF2 (ATF2 Antibody Abstract)
Pathways MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Applikations-hinweise WB: 1:500~1:1000
IHC: 1:50~1:100.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Allgemeine Veröffentlichungen Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

Produkt verwendet in: Waetzig, Seegert, Rosenstiel, Nikolaus, Schreiber: "p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5342-51, 2002 (PubMed).

van Dam, Wilhelm, Herr, Steffen, Herrlich, Angel: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

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