WFDC1 Antikörper (C-Term, His163)

Produktnummer ABIN955571

Produktdetails anti-WFDC1 Antikörper

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Bindungsspezifität: AA 147-177, C-Term, His163

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WFDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects PS20 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 147-177 (H163)amino acids from the C-terminal region of human WFDC1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Andere Bezeichnung: WFDC1 / PS20 (WFDC1 Produkte)

Synonyme: WFDC1 antikoerper, zgc:158671 antikoerper, PS20 antikoerper, 2310058A03Rik antikoerper, ps20 antikoerper, WAP four-disulfide core domain 1 antikoerper, WFDC1 antikoerper, wfdc1 antikoerper, Wfdc1 antikoerper

Hintergrund: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.Synonyms: Prostate stromal protein ps20, WAP four-disulfide core domain protein 1, ps20 growth inhibitor

Gen-ID: 58189

NCBI Accession: NP_067020