SUN2 Antikörper (Middle Region)

Produktnummer ABIN955453

Produktdetails anti-SUN2 Antikörper

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Bindungsspezifität: AA 236-265, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects UNC84B (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 236-265 amino acids from the Central region of human UNC84B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu SUN2

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Andere Bezeichnung: SUN2 / UNC84B (SUN2 Produkte)

Synonyme: UNC84B antikoerper, B230369L08Rik antikoerper, C030011B15 antikoerper, Unc84b antikoerper, RGD1563141 antikoerper, Sad1 and UNC84 domain containing 2 antikoerper, SUN2 antikoerper, Sun2 antikoerper

Hintergrund: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1, MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).Synonyms: FRIGG, KIAA0668, Protein unc-84 homolog B, RAB5IP, Rab5-interacting protein, Rab5IP, SUN domain-containing protein 2, Sad1/unc-84 protein-like 2

Gen-ID: 25777

NCBI Accession: NP_001186508

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion