EFC antikoerper, RFX antikoerper, AI047719 antikoerper, AI385641 antikoerper, zgc:162914 antikoerper, regulatory factor X1 antikoerper, regulatory factor X, 1 (influences HLA class II expression) antikoerper, regulatory factor X, 1a (influences HLA class II expression) antikoerper, RFX1 antikoerper, Rfx1 antikoerper, rfx1a antikoerper
Hintergrund
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.Synonyms: EF-C, Enhancer factor C, MHC class II regulatory factor RFX1, Transcription factor RFX1