PTPN22 Antikörper (C-Term)

Produktnummer ABIN954376

Produktdetails anti-PTPN22 Antikörper

Target: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Bindungsspezifität: AA 662-691, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes PTPN22 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 662-691aa) of human PTPN22.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTPN22

Target: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Andere Bezeichnung: PTPN22 (PTPN22 Produkte)

Synonyme: 70zpep antikoerper, PEP antikoerper, Ptpn8 antikoerper, LYP antikoerper, LYP1 antikoerper, LYP2 antikoerper, PTPN8 antikoerper, protein tyrosine phosphatase, non-receptor type 22 (lymphoid) antikoerper, protein tyrosine phosphatase, non-receptor type 22 antikoerper, Ptpn22 antikoerper, PTPN22 antikoerper

Hintergrund: The PTPN22 gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, LYP1, LYP2, LyP, Lymphoid phosphatase, PEP, PTPN8, Tyrosine-protein phosphatase non-receptor type 22

Gen-ID: 26191

NCBI Accession: NP_001180360