PPARA Antikörper (Middle Region)

Produktnummer ABIN954264

Produktdetails anti-PPARA Antikörper

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Bindungsspezifität: AA 152-181, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse PPAR-alpha (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of Human PPAR-alpha Genename: PPARA

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Andere Bezeichnung: PPAR-alpha (PPARA Produkte)

Synonyme: NR1C1 antikoerper, PPAR antikoerper, PPARalpha antikoerper, hPPAR antikoerper, LOC100136415 antikoerper, PPARALPHA antikoerper, nr1c1 antikoerper, xPPARalpha antikoerper, xppara antikoerper, 4933429D07Rik antikoerper, AW742785 antikoerper, Nr1c1 antikoerper, PPAR-alpha antikoerper, Ppar antikoerper, peroxisome proliferator activated receptor alpha antikoerper, peroxisome proliferator-activated receptor alpha antikoerper, peroxisome proliferator activated receptor alpha L homeolog antikoerper, PPARA antikoerper, LOC100136415 antikoerper, ppara.L antikoerper, Ppara antikoerper, ppara antikoerper

Hintergrund: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.Synonyms: NR1C1, Nuclear receptor subfamily 1 group C member 1, PPAR, PPARA, Peroxisome proliferator-activated receptor alpha

Molekulargewicht: 52225 Da

Gen-ID: 5465

NCBI Accession: NP_001001928

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C