NR4A3 Antikörper (C-Term)

Produktnummer ABIN953751

Produktdetails anti-NR4A3 Antikörper

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Bindungsspezifität: AA 552-582, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR4A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to NR4A3.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 552-582 amino acids from the C-terminal region of human NR4A3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NR4A3

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Andere Bezeichnung: NR4A3 (NR4A3 Produkte)

Synonyme: CHN antikoerper, CSMF antikoerper, MINOR antikoerper, NOR1 antikoerper, TEC antikoerper, AI573420 antikoerper, NOR-1 antikoerper, Nor1 antikoerper, NOR-2 antikoerper, NR4A3 antikoerper, Nr4a3 antikoerper, nuclear receptor subfamily 4 group A member 3 antikoerper, nuclear receptor subfamily 4, group A, member 3 antikoerper, NR4A3 antikoerper, Nr4a3 antikoerper, nr4a3 antikoerper

Hintergrund: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CHN, CSMF, MINOR, Mitogen-induced nuclear orphan receptor, NOR1, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, TEC

Molekulargewicht: 68230 Da

Gen-ID: 8013

NCBI Accession: NP_775292

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway