NKIRAS2 Antikörper (Middle Region)

Produktnummer ABIN953713

Produktdetails anti-NKIRAS2 Antikörper

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Bindungsspezifität: AA 35-64, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKIRAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes human NKIRAS2.

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 35-64aa) of human NKIRAS2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NKIRAS2

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Andere Bezeichnung: NKIRAS2 (NKIRAS2 Produkte)

Synonyme: NKIRAS2 antikoerper, KBRAS2 antikoerper, kappaB-Ras2 antikoerper, zgc:92870 antikoerper, 2410003M04Rik antikoerper, 4930527H08Rik antikoerper, D630018G21Rik antikoerper, NFKB inhibitor interacting Ras like 2 antikoerper, NFKB inhibitor interacting Ras-like 2 antikoerper, NFKB inhibitor interacting Ras like 2 L homeolog antikoerper, NFKB inhibitor interacting Ras-like protein 2 antikoerper, NKIRAS2 antikoerper, Nkiras2 antikoerper, nkiras2 antikoerper, nkiras2.L antikoerper

Hintergrund: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity).Synonyms: KBRAS2, NF-kappa-B inhibitor-interacting Ras-like protein 2

Molekulargewicht: 21508 Da

Gen-ID: 28511

NCBI Accession: NP_001001349