KCNC3 Antikörper (Internal Region)

Produktnummer ABIN952996

Produktdetails anti-KCNC3 Antikörper

Target: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Bindungsspezifität: AA 317-328, Internal Region

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KCNC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-HISNKTVTQA SP

Spezifität: Recognizes KCNC3 / Kv3.3 (317-328).

Kreuzreaktivität (Details): Species reactivity (expected):Human, Pig.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004968.2. Genename: KCNC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KCNC3

Target: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Andere Bezeichnung: KCNC3 (KCNC3 Produkte)

Synonyme: kcnc3-A antikoerper, Kv3.1 antikoerper, KShIIID antikoerper, Kcr2-3 antikoerper, Kv3.3 antikoerper, KSHIIID antikoerper, KV3.3 antikoerper, SCA13 antikoerper, kcnc1 antikoerper, kshiiid antikoerper, kv3.3 antikoerper, sca13 antikoerper, potassium voltage-gated channel subfamily C member 3 antikoerper, potassium channel, voltage gated Shaw related subfamily C, member 1 S homeolog antikoerper, potassium voltage gated channel, Shaw-related subfamily, member 3 antikoerper, potassium channel, voltage gated Shaw related subfamily C, member 3 L homeolog antikoerper, potassium voltage-gated channel, Shaw-related subfamily, member 3 antikoerper, KCNC3 antikoerper, kcnc1.S antikoerper, Kcnc3 antikoerper, kcnc3.L antikoerper

Hintergrund: KCNC3 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.Synonyms: KSHIIID, Potassium voltage-gated channel subfamily C member 3, Voltage-gated potassium channel subunit Kv3.3

Gen-ID: 3748

NCBI Accession: NP_004968