COX7A2L Antikörper (Middle Region)

Produktnummer ABIN951673

Produktdetails anti-COX7A2L Antikörper

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Bindungsspezifität: AA 36-65, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX7A2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to COX7A2L.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 36-65 amino acids from the Central region of human COX7A2L

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu COX7A2L

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Andere Bezeichnung: COX VIIa Related Protein (COX7A2L Produkte)

Synonyme: COX7AR antikoerper, COX7RP antikoerper, EB1 antikoerper, SIG81 antikoerper, SIG-81 antikoerper, Silg81 antikoerper, cytochrome c oxidase subunit 7A2 like antikoerper, cytochrome c oxidase subunit VIIa polypeptide 2-like antikoerper, COX7A2L antikoerper, Cox7a2l antikoerper

Hintergrund: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.Synonyms: COX7A2L, COX7AR, COX7RP, COX7a-related protein, Cytochrome c oxidase subunit 7A-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1

Molekulargewicht: 12615 Da

Gen-ID: 9167

NCBI Accession: NP_004709