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FLIP Antikörper (Middle Region)
CFLAR
Reaktivität: Human
WB, IHC (p), FACS, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-FLIP Antikörper
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Target
Alle FLIP (CFLAR) Antikörper anzeigen
FLIP (CFLAR)
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
Bindungsspezifität
Alle Epitope für FLIP Antikörper
AA 152-182, Middle Region
Reaktivität
Alle Reaktivitäten für FLIP Antikörper
Human
Wirt
Alle Wirte für FLIP Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für FLIP Antikörper
Polyklonal
Konjugat
Alle Konjugate für FLIP Antikörper
Dieser FLIP Antikörper ist unkonjugiert
Applikation
Alle Applikationen für FLIP Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to CFLAR.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Saturated Ammonium Sulfate (SAS) precipitation
Immunogen
KLH conjugated synthetic peptide between 152~182 amino acids from the Center region of human CFLAR
Isotyp
Ig Fraction
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu FLIP
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Target
FLIP (CFLAR)
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
Andere Bezeichnung
CFLAR / Casper / I-FLICE (CFLAR Produkte )
Synonyme
Clarp1 antikoerper, cflar antikoerper, CFLAR antikoerper, FLIP antikoerper, CASH antikoerper, CASP8AP1 antikoerper, CLARP antikoerper, Casper antikoerper, FLAME antikoerper, FLAME-1 antikoerper, FLAME1 antikoerper, I-FLICE antikoerper, MRIT antikoerper, c-FLIP antikoerper, c-FLIPL antikoerper, c-FLIPR antikoerper, c-FLIPS antikoerper, 2310024N18Rik antikoerper, A430105C05Rik antikoerper, Cash antikoerper, ENSMUSG00000072980 antikoerper, Flip antikoerper, Gm9845 antikoerper, c-Flip antikoerper, CASP8 and FADD-like apoptosis regulator a antikoerper, CASP8 and FADD like apoptosis regulator antikoerper, CASP8 and FADD like apoptosis regulator S homeolog antikoerper, CASP8 and FADD-like apoptosis regulator antikoerper, cflara antikoerper, CFLAR antikoerper, cflar antikoerper, cflar.S antikoerper, Cflar antikoerper
Hintergrund
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Molekulargewicht
55344 Da
Gen-ID
8837
NCBI Accession
NP_001120655
Pathways
Apoptose , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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